Nyamiviridae: proposal for a new family in the order Mononegavirales.

Arch Virol

Integrated Research Facility at Fort Detrick (IRF-Frederick), Division of Clinical Research (DCR), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), B-8200 Research Plaza, Fort Detrick, Frederick, MD, 21702, USA,

Published: October 2013

AI Article Synopsis

  • Nyamanini virus (NYMV) and Midway virus (MIDWV) are newly characterized tick-borne viruses that infect land and seabirds, respectively.
  • Both viruses are categorized as nonsegmented, single-stranded negative RNA viruses, showing a close relationship to, but distinction from, other known viruses in the Mononegavirales order.
  • A third virus, soybean cyst nematode virus 1 (SbCNV-1), has been identified as part of this group, leading to a proposal for creating a new family called Nyamiviridae to include all three viruses.

Article Abstract

Nyamanini virus (NYMV) and Midway virus (MIDWV) are unclassified tick-borne agents that infect land birds and seabirds, respectively. The recent molecular characterization of both viruses confirmed their already known close serological relationship and revealed them to be nonsegmented, single- and negative-stranded RNA viruses that are clearly related to, but quite distinct from, members of the order Mononegavirales (bornaviruses, filoviruses, paramyxoviruses, and rhabdoviruses). A third agent, soybean cyst nematode virus 1 (SbCNV-1, previously named soybean cyst nematode nyavirus), was recently found to be an additional member of this new virus group. Here, we review the current knowledge about all three viruses and propose classifying them as members of a new mononegaviral family, Nyamiviridae.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857105PMC
http://dx.doi.org/10.1007/s00705-013-1674-yDOI Listing

Publication Analysis

Top Keywords

order mononegavirales
8
soybean cyst
8
cyst nematode
8
nyamiviridae proposal
4
proposal family
4
family order
4
mononegavirales nyamanini
4
virus
4
nyamanini virus
4
virus nymv
4

Similar Publications

We report a low (38.7%; p<0.0001) level of IgG seroconversion in patients who were positive for measles virus IgM in the Republic of Congo, despite a history of vaccination.

View Article and Find Full Text PDF

Rinderpest and peste des petits ruminants (PPR) are two closely related viral diseases caused by viruses belonging to the genus Morbillivirus and affecting ruminants. Both diseases are notifiable to the World Organisation for Animal Health (WOAH) due to their high contagiosity and economic importance. International collaboration and scientific developments have led to the eradication of rinderpest, which was celebrated in 2011, 250 years after the first veterinary school was created in Lyon.

View Article and Find Full Text PDF

Rinderpest virus and peste des petits ruminants (PPR) virus are highly pathogenic viruses causing disease primarily in cattle and small ruminants, respectively. Although the post-eradication process for rinderpest has been largely successful, gaps in preparedness for a future rinderpest reappearance remain, and the virus is still held in some facilities that have not been registered or inspected, posing a threat to the global community. The PPR Global Eradication Programme will need to overcome significant hurdles to reach a world free of the disease by 2030.

View Article and Find Full Text PDF

Antiviral drugs are essential medications to save the lives of infected people. However, they are under constant threat to become ineffective as viruses evolve quickly. Studying the development of resistance is therefore paramount to understand the impact of mutations on pharmacological treatment and to make informed decisions.

View Article and Find Full Text PDF

The sensitivity of human glioblastoma cells to virus-mediated oncolysis was investigated on five patient-derived cell lines. Primary glioblastoma cells (Gbl13n, Gbl16n, Gbl17n, Gbl25n, and Gbl27n) were infected with tenfold serial dilutions of the Leningrad-3 strain of the mumps virus, and virus reproduction and cytotoxicity were monitored for 96-120 h. Immortalized human non-tumor NKE cells were used as controls to determine the virus specificity.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: