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Surgical Excision and Radiotherapy for Giant Keloids in Auricula: A Case Report.
Int Med Case Rep J
January 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.
Keloids are characterized by excessive growth of fibrous tissue resulting from abnormal wound-healing processes. They may lead to functional impairments, aesthetic deformities, pruritus, and a decreased quality of life. Various therapies, including intralesional corticosteroid injections, cryotherapy, laser therapy, surgical excision, and radiotherapy, have been used to manage keloids, but the recurrence rates remain high.
View Article and Find Full Text PDFCervical Retrieval of Giant Posterior Mediastinal Parathyroid Adenoma with Bizarre Morphology.
Sisli Etfal Hastan Tip Bul
December 2024
Department of Pathology, Izmir Katip Celebi University, Ataturk Training and Research Hospital, Izmir, Türkiye.
Parathyroid adenoma is the most common cause of primary hyperparathyroidism and rarely reaches huge sizes. As the gland enlarges it may exhibit atypical morphology and extension to the mediastinum which may complicate the excision of the tumor while preserving the capsular integrity. We present a 35-year-old male patient who was referred to our department with a complaint of severe hypercalcemia.
View Article and Find Full Text PDFCase report of preservative management of a giant broad ligament fibroid: A challenge in diagnosis and surgery.
Int J Surg Case Rep
January 2025
Department of Gynecology and Obstetrics, University Hospital of Obstetrics and Gynecology in Damascus, Faculty of Medicine, Damascus University, Damascus, Syria.
Introduction: Broad ligament fibroids are unusual types of leiomyomas. They usually present as pelvic masses with pressure-related symptoms. The purpose of this case report is to shed light on the importance of keeping these fibroids in mind when approaching pelvic and abdominal masses, despite their low prevalence.
View Article and Find Full Text PDFA unique presentation of infratemporal fossa giant cell granuloma: A case report and literature review.
Int J Surg Case Rep
January 2025
Department of Otolaryngology Head and Neck Surgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia. Electronic address:
Introduction: The infratemporal fossa (ITF) is considered an uncommon location for giant cell granuloma (GCG), a rare benign disease that is frequently detected in the maxilla and mandible.
Presentation Of Case: A 47-year-old male presented with right-sided hearing loss, tinnitus, and jaw claudication. Radiological imaging confirmed the presence of a mass in the ITF accompanied by bone erosion.
Exploring Denosumab in the Treatment of Giant Cell Tumors: Clinical Evidence and Controversies.
J Craniofac Surg
November 2024
Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL.
Giant cell tumors (GCTs) are benign but locally aggressive bone neoplasms that primarily affect skeletally mature individuals. They are characterized by a tendency for recurrence and being associated with significant morbidity. Traditional treatment has focused on surgical resection; however, the role of medical therapies, such as Denosumab, a bone anti-resorptive drug, which has been Food and Drug Administration (FDA)-approved for unresectable GCTs since 2013, recently has gained prominence.
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