We report a unique case of successfully performed intraluminal brachytherapy for low volume urethral mucosal recurrence of transitional cell carcinoma urinary bladder, initially treated by transurethral resection of bladder tumor, followed by radical cystectomy. Since the patient was unwilling to undergo any other operational interventions, intraluminal brachytherapy of urethra was attempted. Fluroscopy guided intraluminal HDR brachytherapy using Lumencath(®) catheter under local anesthesia, and remote afterloading system (Nucletron, an Elekta company, Elekta AB, Stockholm, Sweden) was performed. A fraction dose of 7 Gy in seven weekly fractions was prescribed at 0.5 cm from the single applicator. The result was promising in terms of local control and symptomatic relief. Therefore, intraluminal brachytherapy in low volume superficial local disease in urethra may play a potential role, and should be applied when repeated surgery is not feasible due to technical or medical reasons.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635051PMC
http://dx.doi.org/10.5114/jcb.2013.34451DOI Listing

Publication Analysis

Top Keywords

intraluminal brachytherapy
12
recurrence transitional
8
transitional cell
8
cell carcinoma
8
carcinoma urinary
8
urinary bladder
8
brachytherapy low
8
low volume
8
intraluminal
5
brachytherapy
5

Similar Publications

Article Synopsis
  • The study aimed to create and assess EMVision, a system utilizing electromagnetic tracking technology to enhance the placement of brachytherapy applicators, focusing on procedure quality and efficiency.
  • EMVision integrates CT imaging and EMT reference frames for precise needle placement, using an automated system that displays real-time 3D visuals and adjusts for anatomy shifts during the procedure.
  • Results showed EMVision achieved high accuracy in needle placement, both in phantom tests and human cadaver evaluations, suggesting its potential to streamline brachytherapy procedures and improve training outcomes.
View Article and Find Full Text PDF

Background And Purpose: The upgrade of major equipment can be disruptive to clinical operations and introduce risk as policy and procedures need to adapt to new technical possibilities and constraints. We describe here the transition from GammaMedPlus-iX to Bravos in a busy brachytherapy clinic, involving four afterloaders across two sites.

Material And Methods: Our clinic employs three high-dose-rate remote afterloaders in four dedicated treatment vaults at the main site and a fourth afterloader at a regional location.

View Article and Find Full Text PDF

Lung cancer is the leading cause of cancer death worldwide. It may present as airway obstruction in a patient with endobronchial masses. Endobronchial brachytherapy (EBBT) has been shown to provide palliative therapy.

View Article and Find Full Text PDF

Cholangiocarcinoma (CCA) are primary malignancies of biliary system and usually unresectable at the time of diagnosis. As a consequence, majority of these cases are candidates for palliative care. With the advances in chemotherapeutic agents and multidisciplinary care, the survival rate has improved in cases with inoperable malignant biliary obstruction.

View Article and Find Full Text PDF

The black hole (BH) phenomenon is an intraluminal restenotic lesion. It was identified by intravascular ultrasound (IVUS) and optical coherence tomography (OCT) after intracoronary brachytherapy and drug-eluting stent implantation. Despite the similarity in the mode of action of brachytherapy and drug-eluting stent implantation, the BH phenomenon appears to be uncommon after drug-eluting stent implantation.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!