AI Article Synopsis
- The crystal structure of the cyclic tetrapeptide cyclo(Gly-L-Ser-L-Pro-L-Glu) [cyclo(GSPE)] was determined.
- The synthesized cyclo(GSPE) forms a complex with lead ion in a 1:1 ratio, indicating a specific coordination.
- This marks the first instance of a heavy metal ion polymerizing with a rigid cyclic tetrapeptide, creating a new type of macrocyclic complex.
Article Abstract
The crystal structure of a naturally occurring cyclic tetrapeptide cyclo(Gly-L-Ser-L-Pro-L-Glu) [cyclo(GSPE)] was obtained. The conformation of synthesized cyclo(GSPE) fixes the coordination to lead ion in a 1:1 ratio. This cyclo(GSPE)-Pb complex was constructed as an asymmetric 3D network in the crystalline state. The polymerization of a heavy metal ion with a rigid asymmetric cyclic tetrapeptide represents the first example of a new class of macrocyclic complexes.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270303 | PMC |
| http://dx.doi.org/10.3390/molecules18054972 | DOI Listing |
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