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Medical cyber crises and biotechnological syndromes: a multisite clinical simulation study focused on digital health complaints.
Lancet
November 2023
Institute of Health Informatics, University College London, London, UK.
Article Synopsis
- Biotechnological syndromes are health issues that arise from the combination of human biology and digital technology, manifesting through device malfunctions and cyber abuse.
- A study was conducted using clinical simulations to assess how well physicians can respond to these syndromes, identify gaps in their training, and recognize real-world cases stemming from digital tech.
- Results showed that participants cited various issues in their practices, such as device malfunctions and inadequate training, highlighting significant barriers to effectively diagnosing and treating technology-related health problems.
Runaway pacemaker.
BMJ Case Rep
March 2019
Department of Cardiology, Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea, UK.
Runaway pacemaker is phenomenon in which pacemaker induces ventricular tachycardia as a result of some malfunction in the device. This entity is not very common in clinical practice. Normally, the pacemaker perceives the inherent cardiac impulse and hence averting the delivery of pacemaker stimulus in susceptible period of cardiac cycle.
View Article and Find Full Text PDFSurvival and weak chaos.
R Soc Open Sci
May 2018
The Braithwaite Group in: Department of Ecosystem Science and Management, The Pennsylvania State University, 410 Forest Resources Building, University Park, PA 16802, USA.
Survival analysis in biology and reliability theory in engineering concern the dynamical functioning of bio/electro/mechanical units. Here we incorporate effects of chaotic dynamics into the classical theory. Dynamical systems theory now distinguishes strong and weak chaos.
View Article and Find Full Text PDFCalmodulin regulates Ca3 T-type channels at their gating brake.
J Biol Chem
December 2017
Biology, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada. Electronic address:
Calcium (Ca1 and Ca2) and sodium channels possess homologous CaM-binding motifs, known as IQ motifs in their C termini, which associate with calmodulin (CaM), a universal calcium sensor. Ca3 T-type channels, which serve as pacemakers of the mammalian brain and heart, lack a C-terminal IQ motif. We illustrate that T-type channels associate with CaM using co-immunoprecipitation experiments and single particle cryo-electron microscopy.
View Article and Find Full Text PDFInappropriate high-rate pacing with maximal output due to runaway pacemaker malfunction in a temporary device.
Europace
August 2016
Cardiovascular Center, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea
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