The synthesis of new ribo and 2'-β-C-methyl ribo Janus type nucleosides J-AA, J-AG and J-AU is reported along with their ability to block HCV and HIV replication. Their toxicity was also assessed in Huh7, human lymphocytes, CEM and Vero cells.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704321 | PMC |
| http://dx.doi.org/10.1016/j.bmcl.2013.03.077 | DOI Listing |
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