AI Article Synopsis
- Physicians need to quickly diagnose poisonings, but comprehensive data on toxic substances in France is lacking.
- This study retrospectively analyzed substances reported in poisonings at Lariboisière hospital's ICU in 2011, categorizing them into medicinal and non-medicinal products.
- Out of 315 patients, 891 substances were reported, with 83% being medicinal (mainly for the nervous and cardiovascular systems) and 13% being recreational/addictive drugs, highlighting the need for better education in toxicology.
- Future studies aim to create a comprehensive observatory for substances involved in poisoning to inform treatment and educational programs.
Article Abstract
Introduction: To treat poisonings, physicians must rapidly make a diagnosis. As of today, exhaustive data on most frequently reported toxics are not available in France.
Materials And Methods: This was a retrospective study of announced substances at patients' admissions in intensive care unit for poisoning in 2011 at Lariboisière hospital. Announced substances were collected from anamnesis reported in patient medical records. Verbatims were harmonized and substances classified in medicinal products and three categories of non-medicinal products (recreational/addictive drugs, others, unknown nature).
Results: Three hundred and fifteen patients were included, with 891 announced specified substances corresponding to 198 different verbatims. Most of them (83%) are medicinal products (mainly nervous and cardiovascular system molecules). There were 13% of recreational/addictive substances, 3% of other non-medicinal substances. Of the occurrences, 1.5% represent unknown substances.
Discussion: These substances supposedly used in poisoning should be included in toxicology learning programs. Their dosage should be possibly performed in routine by toxicology laboratories.
Conclusion: An ongoing study in a prospective and retrospective manner will become an observatory of the substances involved in poisoning.
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| http://dx.doi.org/10.1016/j.pharma.2013.02.002 | DOI Listing |
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