Response to comment on "In monkeys making value-based decisions, LIP neurons encode cue salience and not action value".

Newsome et al. question neither our key result, that large-penalty cues elicited stronger responses than small-penalty cues, nor our key conclusion, that neurons early in the trial signaled cue salience and not action value. Instead, they focus on subsequent neuronal activity. The patterns of delay-period activity that they note can be explained by reference to experimental methodology.