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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674442 | PMC |
| http://dx.doi.org/10.1038/embor.2013.54 | DOI Listing |
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Objective: Hypoxic-ischemic brain damage (HIBD) is a leading cause of neonatal mortality, resulting in brain injury and persistent seizures that can last into the late neonatal period and beyond. Effective treatments and interventions for infants affected by hypoxia-ischemia remain lacking. Clinical investigations have indicated an elevation of nuclear factor of activated T cells 5 (NFAT5) in whole blood from umbilical cords of severely affected HIBD infants with epilepsy.
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Are the membrane systems able of performing arithmetic operations? In the last dozen years, there were published several implementations of the arithmetic operations based on membrane systems by using all available topologies (cell-like, tissue-like, or neural-like). In particular, the spiking neural P systems perform arithmetic operations by using the numbers represented in binary base. In this paper, we consider numbers represented in unary base (to each number n corresponds an object with multiplicity n), and we propose two encodings for the main arithmetic operations (addition, subtraction, multiplication and division) between numbers given in unary base: (i) for each pair of input values generate an instance of a spiking neural P system with astrocytes producing calcium with rules based on these values; (ii) generate a spiking neural P system with astrocytes producing calcium that does not depend on these values.
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Article Synopsis
- * This study developed and characterized iron nanoparticles doped with selenium (FeNP@SeNPs) to explore their effects on the calcium signaling system in astrocytes under ischemia-like conditions.
- * The research found that combining magnetic selenium nanoparticles with electromagnetic stimulation enhances cell penetration and facilitates endocytosis through TRPV4 channel activation, allowing for a reduced effective concentration compared to traditional selenium nanoparticles.
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