Objectives: The objectives of this study were to assess whether high exposure to the Canada Prenatal Nutrition Program (CPNP) improved 1) the personal health practices, such as smoking and breastfeeding, of participants and 2) birth outcomes, such as low birth weight and preterm birth.
Intervention: The CPNP is a population-level health intervention that aims to contribute to improved health outcomes for pregnant women and their newborn children facing conditions of risk. The program, which is jointly managed by the federal and provincial governments, serves more than 45,000 Canadian women annually.
Participants: Participants were women who entered the program prenatally in 2002-2006 and were socially, demographically and geographically diverse. Almost 12% were adolescents, and almost 10% were over 34 years of age; 5% were recent immigrants (in Canada <10 years), and close to one quarter were Aboriginal.
Setting: This comprised a broad range of community-based projects in 2,000 communities.
Outcomes: Descriptive statistics showed that the CPNP is reaching the women for which it is intended. Participants with high CPNP exposure were more likely to reduce the number of cigarettes they smoked, to cease drinking, to breastfeed their infants and to breastfeed for longer, and to increase their use of vitamin/mineral supplements from never to daily. Furthermore, they were less likely to give birth to an infant that was preterm, had low birth weight, was small for gestational age or had poor neonatal health. Unexpectedly, participants were more likely to give birth to a large-for-gestational-age infant. Our stratified "equity" analyses showed some variation by social group, indicating that the benefits were not consistently shared by all.
Conclusion: High CPNP exposure improved the health behaviours and birth outcomes of women and their newborn children facing conditions of risk. Furthermore, our equity analysis found that the associations between higher CPNP exposure and healthy behaviour changes, and even more so, better birth outcomes, were generally found across many social groups. In the absence of a control group, the study used an innovative approach to estimating the impact of the CPNP by comparing those who received a higher "dose" with those receiving a lower dose of CPNP services.
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http://dx.doi.org/10.1007/BF03404456 | DOI Listing |
J Int AIDS Soc
February 2025
Centre for Integrated Data and Epidemiological Research, School of Public Health, University of Cape Town, Cape Town, South Africa.
Introduction: Sexually transmitted infections (STIs) in pregnancy are associated with an increased risk of vertical HIV transmission and adverse pregnancy and birth outcomes. In South Africa, syndromic management is the standard of care for STI management. We assessed the potential impact of point-of-care (POC) screening for curable STIs (Chlamydia trachomatis [CT], Trichomonas vaginalis [TV] and Neisseria gonorrhoeae [NG]) during pregnancy on vertical HIV transmission and adverse pregnancy and birth outcomes.
View Article and Find Full Text PDFAust N Z J Obstet Gynaecol
January 2025
Reproductive Services Unit, The Royal Women's Hospital, Parkville, Australia.
Background: Modern assisted reproductive technology (ART), including pre-implantation genetic testing for aneuploidy (PGT-A), has opened new avenues in understanding early embryonic events and has simultaneously raised questions about the impact of ART itself on sex ratios.
Aims: The primary aim was to investigate whether patient demographic characteristics, ovarian stimulation protocols or laboratory characteristics in ART influence sex ratios. The secondary aim was to relate the blastocyst sex ratio (BSR) to the corresponding secondary sex ratio (SSR) in our patient cohort.
J Obstet Gynaecol Res
February 2025
Sleep Center, Kuwamizu Hospital, Kumamoto, Japan.
Background: Pregnancy-related anatomic, physiologic, and hormonal factors can occur at different stages of pregnancy and affect sleep disturbances. The relationship between sleep problems during pregnancy and postpartum depressive symptoms as well as neonatal condition at delivery have not been well described. This study hypothesized that sleep problems are associated with postpartum depressive symptoms and adverse neonatal outcomes at delivery.
View Article and Find Full Text PDFInt J Gynaecol Obstet
January 2025
Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu, People's Republic of China.
Background: In 2013, The Cancer Genome Atlas Research Network suggested that endometrial carcinoma patients may be reclassified into four molecular prognostic groups.
Objective: To compare survival of endometrial carcinoma patients with different mutational profiles.
Search Strategy: Studies reporting survival of endometrial carcinoma patients were identified through systematic searches of four databases.
J Perinatol
January 2025
University of California, San Diego, Rady Children's Hospital of San Diego, La Jolla, CA, USA.
Objective: Evaluate the changes in management and outcomes of Californian infants with hypoxic ischemic encephalopathy (HIE).
Study Design: Infants with HIE were identified from a California administrative birth cohort using ICD codes and divided into two epochs, Epoch 1 (2010-2015) and Epoch 2 (2016-2019). Risk ratios (RR) for induced hypothermia (IH) in each epoch and their outcomes were calculated using log-linear regression.
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