Case report: imaging features in a renal transplant patient with calcineurin inhibitor-induced pain syndrome (CIPS).

Skeletal Radiol

Department of Radiology and Radiological Science, Medical University of South Carolina, 96 Jonathan Lucas Street, MSC 323, Charleston, SC 29425, USA.

Published: September 2013

AI Article Synopsis

  • Post-transplant distal limb bone marrow edema syndrome (CIPS) is a painful condition affecting 2-14% of kidney transplant patients, often triggered by calcineurin inhibitors like cyclosporine and tacrolimus.
  • A case is presented of a patient developing CIPS 73 days post-kidney transplant, highlighting relevant imaging findings.
  • The authors aim to differentiate CIPS as a unique syndrome, noting it hasn't been clearly defined in radiology literature yet.

Article Abstract

Post-transplant distal limb bone marrow edema syndrome or calcineurin inhibitor-induced pain syndrome (CIPS) is generally a self-limiting but debilitating acute pain syndrome that has been reported in 2-14 % of renal transplant recipients. The disease is extensively described in the transplant literature in patients receiving the calcineurin inhibitors cyclosporine and tacrolimus. We present a case of CIPS arising in a patient 73 days after renal allograft, review the imaging findings, and discuss proposed etiologies and differential diagnoses. To the authors' knowledge, CIPS has not been characterized as a distinct entity in the radiology literature.

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Source
http://dx.doi.org/10.1007/s00256-013-1616-5DOI Listing

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