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| http://dx.doi.org/10.2337/dc12-2248 | DOI Listing |
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Hypoxic conditions affect transcriptome of endometrial stromal cells in endometriosis and promote TGFBI axis.
Front Endocrinol (Lausanne)
January 2025
Celvia CC AS, Tartu, Estonia.
Background: Endometriosis is characterized by the ectopic growth of endometrial-like cells, causing chronic pelvic pain, adhesions and impaired fertility in women of reproductive age. Usually, these lesions grow in the peritoneal cavity in a hypoxic environment. Hypoxia is known to affect gene expression and protein kinase (PK) activity.
View Article and Find Full Text PDFAssociation between menstrual cycle pattern regularity and changes in menstrual bleeding following COVID-19 vaccination: secondary analysis of an observational study.
BMJ Sex Reprod Health
December 2024
Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, Oregon, USA.
Pregnancy with Wilson's Disease: A Case Series.
Mymensingh Med J
January 2025
Dr Mousumi Saha, Assistant Professor, Fetomaternal Medicine Subspeciality (FCPS) Course Student, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail:
Wilson's disease is an autosomal recessive disorder that affects copper transport due to deficiency of ceruloplasmin and causes deposition of copper mainly in the liver, brain and cornea. It causes hepatic and/or neuropsychiatric manifestations. This copper deposition causes cirrhosis of the liver, encephalopathy and liver failure.
View Article and Find Full Text PDFIncreased ferritin with contraceptives containing ethinyl estradiol drospirenone in polycystic ovary syndrome: a paradox of iron storage and iron deficiency.
Endocrine
December 2024
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Health Sciences, Kartal Dr. Lutfi Kirdar City Hospital, Kartal, Istanbul, Turkey.
Objectives: The relationship between elevated ferritin levels and metabolic abnormalities in PCOS patients, and whether ferritin is a cause or a consequence, is still debated. This study aimed to evaluate the impacts of the fourth generation combined oral contraceptive containing ethinyl estradiol/drospirenone (EE 30 mcg/DRSP 3 mg), known for its favorable metabolic profile and lower side effect risk, on iron metabolism in PCOS patients, while also exploring the potential relationship between metabolic parameters and iron status.
Methods: The retrospective analysis was conducted on 81 women aged 18-45, diagnosed with PCOS according to the Rotterdam criteria and treated with EE/DRSP for six months.
Effect of eccentric-based resistance exercise on bone (re)modelling markers across the menstrual cycle and oral contraceptive cycle.
Eur J Appl Physiol
December 2024
LFE Research Group, Department of Health and Human Performance. Faculty of Physical Activity and Sport Sciences, Universidad Politécnica de Madrid, Calle de Martín Fierro, 7, 28040, Madrid, Spain.
Purpose: To investigate the acute effects of eccentric-based resistance exercise and sex-hormone fluctuations on P1NP and β-CTX-1 concentrations in premenopausal females.
Methods: Nine eumenorrheic females and ten oral contraceptive (OC) users performed eccentric-based resistance exercise, consisted of 10 × 10 repetitions of parallel back squats with a 4-s eccentric phase, in the early-follicular (EFP), late-follicular (LFP) and mid-luteal (MLP) phases of the menstrual cycle (MC) or in the withdrawal (WP) and active pill-taking (APP) phases of the OC cycle.
Results: 17β-oestradiol (pg·ml) was lower in EFP (36.
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