[Clinicopathologic characteristics of primary thyroid-like follicular carcinoma in kidney].

Zhonghua Bing Li Xue Za Zhi

Department of Pathology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.

Published: January 2013

Objective: To explore the clinicopathological characteristics of primary thyroid-like follicular carcinoma of the kidney.

Methods: A case of primary thyroid-like follicular carcinoma of the kidney was studied with histology and immunohistochemical staining, and its clinical and pathological findings were further analyzed with review of the literature.

Results: The patient was a 26-year-old asymptomatic woman who had a kidney mass during her annual physical examination. The tumor was well-circumscribed. Pathologically, the tumor showed follicular structures with colloid-like material in the lumina. Immunohistochemically, the tumor cells showed intense staining for CK7 and vimentin and negative for thyoid transcripation factor-1, thyroglobulin, thyoid peroxidase and RCC.

Conclusions: The diagnosis of primary thyroid-like follicular carcinoma of the kidney is based on the characteristic follicular architecture with colloid-like material, and the metastasis from a thyroid follicular carcinoma must be excluded clinically and pathologically before making the final diagnosis.

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Source
http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2013.01.008DOI Listing

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