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Studying the Potential Effects of Artificial Intelligence on Physician Autonomy: Scoping Review.
JMIR AI
March 2025
Department of Health Economics and Health Care Management, School of Public Health, Bielefeld University, Bielefeld, Germany.
Background: Physician autonomy has been found to play a role in physician acceptance and adoption of artificial intelligence (AI) in medicine. However, there is still no consensus in the literature on how to define and assess physician autonomy. Furthermore, there is a lack of research focusing specifically on the potential effects of AI on physician autonomy.
View Article and Find Full Text PDFThis case report describes the co-occurrence of an atypical presentation of gingival papillary hyperplasia and intrahepatic cholangiocarcinoma in a patient with HIV. The article also highlights the role of dentists in the multidisciplinary management of patients with HIV and emphasizes the need for clinicians to perform a thorough review of systems and laboratory test findings. Such information, in addition to findings on oral examination, could aid in the diagnosis of systemic diseases and prompt early referral to treating physicians.
View Article and Find Full Text PDFDoravirine/islatravir (100/0.75 mg) once-daily compared to bictegravir/emtricitabine/tenofovir alafenamide as initial HIV-1 treatment: 48-week results from a phase 3, randomized, controlled, double-blind, non-inferiority trial.
Clin Infect Dis
March 2025
Merck & Co., Inc., Rahway, NJ, USA.
Background: Doravirine/islatravir is an investigational, once-daily regimen being studied for HIV-1 treatment.
Methods: In this phase 3, double-blind, non-inferiority trial, previously untreated people with HIV-1 (≥18 years) were randomized (1:1) and stratified by HIV-1 RNA (≤/>100,000 copies/mL) and CD4 count ( View Article and Find Full Text PDF
Optimizing the efficiency and effectiveness of data quality assurance in a multicenter clinical dataset.
J Am Med Inform Assoc
March 2025
Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON M5C 3G7, Canada.
Objectives: Electronic health records (EHRs) data are increasingly used for research and analysis, but there is little empirical evidence to inform how automated and manual assessments can be combined to efficiently assess data quality in large EHR repositories.
Materials And Methods: The GEMINI database collected data from 462 226 patient admissions across 32 hospitals from 2021 to 2023. We report data quality issues identified through semi-automated and manual data quality assessments completed during the data collection phase.
Monogenic Common Variable Immunodeficiency (Mo-CVID) Score for Optimizing the Genetic Diagnosis in Pediatric CVID Cohort.
Eur J Immunol
March 2025
Department of Health Sciences, University of Florence, Florence, Italy.
Common variable immunodeficiency (CVID) represents an "umbrella" diagnosis due to its clinical and immunological heterogeneity. The primary objective of this study was to describe a cohort of CVID pediatric subjects from clinical, immunological, and genetic viewpoints. Secondary, we propose a model for prioritizing genetic investigations in these patients.
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