Theoretical study of free space coupling to high-Q whispering gallery modes (WGMs) are presented in circular and deformed microcavities. Both analytical solutions and asymptotic formulas are derived for a circular cavity. The coupling efficiencies at different coupling regimes for cylindrical incoming wave are discussed, and the maximum efficiency is estimated for the practical Gaussian beam excitation. In the case of a deformed cavity, the coupling efficiency can be higher than the circular cavity if the excitation beam can match the intrinsic emission which can be tuned by adjusting the degree of deformation. Employing an abstract model of slightly deformed cavity, we find that the asymmetric and peak like line shapes instead of the Lorentz-shape dip are universal in transmission spectra due to multi-wave interference, and the coupling efficiency cannot be estimated from the absolute depth of the dip. Our results provide guidelines for free space coupling in experiments, suggesting that the high-Q asymmetric resonator cavities (ARCs) can be efficiently excited through free space which will stimulate further experiments and applications of WGMs based on free space coupling.
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http://dx.doi.org/10.1364/OE.21.009982 | DOI Listing |
J Med Chem
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Medicinal Chemistry and Bioinformatics Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
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Department of Oncology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
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View Article and Find Full Text PDFActa Crystallogr A Found Adv
March 2025
Department of Physics, Durham University, South Road, Durham, DH1 3LE, United Kingdom.
Bloch waves are often used in dynamical diffraction calculations, such as simulating electron diffraction intensities for crystal structure refinement. However, this approach relies on matrix diagonalization and is therefore computationally expensive for large unit cell crystals. Here Bloch wave theory is re-formulated using the physical optics concepts underpinning the multislice method.
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Department of Chemical and Biomolecular Engineering, North Carolina State University Raleigh North Carolina 27606 USA
Plastic pollution, particularly microplastics (MPs), poses a significant global threat to ecosystems and human health, necessitating innovative remediation strategies. Biocompatible and biodegradable plastic-binding peptides (PBPs) offer a potential solution through targeted adsorption and subsequent MP detection or removal from the environment. A challenge in discovering plastic-binding peptides is the vast combinatorial space of possible peptides (, over 10 for 12-mer peptides), which far exceeds the sample sizes typically reachable by experiments or biophysics-based computational methods.
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January 2025
Department of Chemistry and Chemical Biology, Stevens Institute of Technology 1 Castle Point Terrace Hoboken NJ 07030 USA
Engineered heme proteins possess excellent biocatalytic carbene N-H insertion abilities for sustainable synthesis, and most of them have His as the Fe axial ligand. However, information on the basic reaction mechanisms is limited, and ground states of heme carbenes involved in the prior computational mechanistic studies are under debate. A comprehensive quantum chemical reaction pathway study was performed for the heme model with a His analogue as the axial ligand and carbene from the widely used precursor ethyl diazoacetate with aniline as the substrate.
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