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Outcomes of a transapical edge-to-edge repair system in secondary mitral regurgitation.
J Invasive Cardiol
January 2025
Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, China; State Key Laboratory of Cardiovascular Diseases, Zhongshan Hospital, Fudan University; NHC Key Laboratory of Ischemic Heart Diseases; Key Laboratory of Viral Heart Diseases, Chinese Academy of Medical Sciences; National Clinical Research Center for Interventional Medicine, Shanghai, China.
Objectives: The ValveClamp system (Hanyu Medical Technology) is a novel transcatheter edge-to-edge repair (TEER) system designed for ease of operation; however, there is a lack of data on its application in secondary mitral regurgitation (SMR). The authors report the mid-term outcomes of TEER using the ValveClamp system in SMR.
Methods: The study prospectively analyzed consecutive severe SMR patients who underwent transapical ValveClamp implantation at 10 Chinese centers.
Transfemoral Compared to Transapical Transcatheter Aortic Valve Implantation in Chronic Dialysis-Dependent Patients.
J Clin Med
December 2024
Herzzentrum Dresden, Department of Internal Medicine and Cardiology, Technische Universität Dresden, Fetscherstr. 76, 01307 Dresden, Germany.
Patients with end-stage kidney disease (ESRD) represent a high-risk population in terms of both development of and death by cardiovascular diseases. Outcome data of ESRD patients with severe aortic valve stenosis (AS) treated by transcatheter aortic valve implantation (AVI) are scarce. We aim to compare the outcome of ESRD patients undergoing transfemoral (TF) or transapical (TA) AVI.
View Article and Find Full Text PDFEarly Feasibility Study with the SATURN Transapical Mitral Valve Replacement Device.
Ann Thorac Surg Short Rep
December 2024
Department of Cardiac Surgery, San Raffaele University Hospital, Milano, Italy.
Purpose: To report the outcomes of the early feasibility study of transapical transcatheter mitral valve replacement (TMVR) with the SATURN System (InnovHeart, Milano, Italy) to treat patients with severe functional mitral regurgitation.
Description: Five high surgical risk patients underwent transapical transcatheter mitral valve replacement with the SATURN System at a single center. One-year follow-up is complete for all patients.
Clinical feasibility study of transcatheter edge-to-edge mitral valve repair in dogs with the canine V-Clamp device.
Front Vet Sci
December 2024
Department of Clinical Sciences and James L. Voss Veterinary Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States.
Objective: To determine procedural feasibility, safety, and short-term efficacy in dogs with severe degenerative mitral regurgitation (MR) undergoing transcatheter edge-to-edge repair (TEER) with a canine-specific device.
Design: Prospective, single-arm (uncontrolled), single-institution clinical feasibility study.
Animals: Fifty client-owned dogs with severe degenerative MR operated over a 28-month period.
Article Synopsis
- - Mitral regurgitation (MR) is the second most common heart valve disease, and severe cases often require surgical intervention, though high-risk patients may need alternative treatments like transcatheter edge-to-edge valve repair or the Tendyne valve.
- - The Tendyne valve, which can be implanted without traditional surgery, showed promising results: 93.2% of patients had no MR after treatment, and heart failure hospitalizations significantly decreased post-surgery.
- - An economic analysis indicated that using the Tendyne valve is cost-effective compared to medications, with a favorable cost per quality-adjusted life year, and around 60 patients annually could benefit from this treatment in Poland.
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