In this study, we investigated and modeled the performance of target pointing hand movements in a hand free, touchless 3D environment. The targets had different positions, sizes and distances. Performance measurements included total movement time and movement trajectories. The total movement time consisted of a "primary submovement time" and a "secondary submovement time". Results indicated that the total movement time for targets with depth in the upper part of the spherical framework (3.10s) was shorter than for targets without depth (3.79s). The time for targets without depth in the lower part of the spherical framework (2.94s) was shorter than for targets with depth (3.57s). Within a 3D perspective display, the perception of distance and size depends on its depth position. Our results confirmed the adequacy of the 3D information in the display by showing the longest total movement time was observed for the reach of the "forward" target (3.94s). Fitts' model explained the total movement time (for targets without depth r(2)=.72; for targets with depth r(2)=.72). This study showed that participants navigated the 3D space naturally and could move the cursor using both sequential a axis moving strategy and a straight line moving strategy. Real-life applications of the proposed method include interface design for 3D perspective displays and hand movements in 3D environments.
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http://dx.doi.org/10.1016/j.humov.2012.02.001 | DOI Listing |
Kidney Int
January 2025
Laboratório de Fisiopatologia Renal (LIM 16), Nephrology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), Universidade de São Paulo, São Paulo, Brazil. Electronic address:
In 2017, Kidney Disease: Improving Global Outcomes (KDIGO) published a Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). Since then, new lines of evidence have been published related to evaluating disordered mineral metabolism and bone quality and turnover, identifying and inhibiting vascular calcification, targeting vitamin D levels, and regulating parathyroid hormone. For an in-depth consideration of the new insights, in October 2023, KDIGO held a Controversies Conference on CKD-MBD: Progress and Knowledge Gaps Toward Personalizing Care.
View Article and Find Full Text PDFBMC Cancer
January 2025
Department of Radiation Oncology, First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming, 650032, P. R. China.
Introduction: The core objective of this study was to precisely locate metastatic lymph nodes, identify potential areas in nasopharyngeal carcinoma patients that may not require radiotherapy, and propose a hypothesis for reduced target volume radiotherapy on the basis of these findings. Ultimately, we reassessed the differences in dosimetry of organs at risk (OARs) between reduced target volume (reduced CTV2) radiotherapy and standard radiotherapy.
Methods And Materials: A total of 209 patients participated in the study.
Commun Biol
January 2025
Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
Aedes mosquitoes transmit pathogenic arthropod-borne (arbo) viruses, putting nearly half the world's population at risk. Blocking virus replication in mosquitoes is a promising approach to prevent arbovirus transmission, the development of which requires in-depth knowledge of virus-host interactions and mosquito immunity. By integrating multi-omics data, we find that heat shock factor 1 (Hsf1) regulates eight small heat shock protein (sHsp) genes within one topologically associated domain in the genome of the Aedes aegypti mosquito.
View Article and Find Full Text PDFSci Rep
January 2025
School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan, 316022, People's Republic of China.
Accurate and rapid segmentation of key parts of frozen tuna, along with precise pose estimation, is crucial for automated processing. However, challenges such as size differences and indistinct features of tuna parts, as well as the complexity of determining fish poses in multi-fish scenarios, hinder this process. To address these issues, this paper introduces TunaVision, a vision model based on YOLOv8 designed for automated tuna processing.
View Article and Find Full Text PDFAnal Chim Acta
February 2025
Department of Chemistry, University of Waterloo, Waterloo, ON, Canada. Electronic address:
Background: Normothermic ex situ heart perfusion (ESHP) has emerged as a valid modality for advanced cardiac allograft preservation and conditioning prior to transplantation though myocardial function declines gradually during ESHP thus limiting its potential for expanding the donor pool. Recently, the utilization of dialysis has been shown to preserve myocardial and coronary vasomotor function. Herein, we sought to determine the changes in myocardial metabolism that could support this improvement.
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