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Impact of pandemic service changes on ethnic inequalities in maternal and perinatal outcomes in England: a population-based study.
BMJ Open
January 2025
Centre for Primary Care and Public Health, Queen Mary University of London Wolfson Institute of Preventive Medicine, London, UK.
Objective: In the UK and worldwide, there are substantial ethnic inequalities in maternal and perinatal care and outcomes. We aim to assess the impact of the unprecedented change in care provision during the COVID-19 pandemic on inequalities in adverse maternity outcomes.
Design: Retrospective cohort study using structured electronic health record data.
Biomarkers.
Alzheimers Dement
December 2024
Weill Cornell Medicine, New York, NY, USA; St Vincent's Hospital, Melbourne, VIC, Australia.
Background: Postoperative delirium (POD) is a serious complication of surgery associated with prolonged hospitalisation, long-term cognitive decline, dementia and mortality. There is increasing evidence that electroencephalography (EEG) monitoring may reduce the incidence of POD, however, the best method for achieving this is unclear.
Method: This presentation will present the results of a multicentre randomised clinical trial of 515 at-risk patients undergoing major surgery from 8 centres in 3 countries who were assessed for POD for 5 days postoperatively.
Background: Mild traumatic brain injury (mTBI) increases dementia risk. Delays in diagnosis are common due to insensitive tools, prolonging symptoms and time to treatment. Dual-task gait and functional mobility deficits are present post-mTBI and in people living with dementia (PWD); however, it is unclear whether dual-tasking can be used as a tool to differentiate between groups.
View Article and Find Full Text PDFDistinctive Delta and Theta Responses in Deductive and Probabilistic Reasoning.
Brain Behav
January 2025
Research Institute for Health Sciences and Technologies (SABITA), Neuroscience Research Center, Clinical Electrophysiology, Neuroimaging and Neuromodulation Lab, Istanbul Medipol University, Istanbul, Turkey.
Introduction: The neural substrates of reasoning, a cognitive ability we use constantly in daily life, are still unclear. Reasoning can be divided into two types according to how the inference process works and the certainty of the conclusions. In deductive reasoning, certain conclusions are drawn from premises by applying the rules of logic.
View Article and Find Full Text PDFInterconnected pathways link faecal microbiota plasma lipids and brain activity to childhood malnutrition related cognition.
Nat Commun
January 2025
Division of Developmental Medicine, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Malnutrition affects over 30 million children annually and has profound immediate and enduring repercussions. Survivors often suffer lasting neurocognitive consequences that impact academic performance and socioeconomic outcomes. Mechanistic understanding of the emergence of these consequences is poorly understood.
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