Despite remarkable advances in the care of patients with laryngeal cancer over the past several decades, including a growing awareness of therapeutic complications and attention to quality of life, little is known about the causes of mortality in this population. In addition to the laryngeal malignancy itself, acute and late or chronic treatment-associated causes, second primary cancers, intercurrent disease and psychosocial factors are all responsible for patient morbidity and mortality. We examine the current literature related to the causes of death in patients with laryngeal cancer, in the hope of guiding future interventions to improve the longevity and quality of life of individuals with this cancer.
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http://dx.doi.org/10.1007/s00405-013-2478-0 | DOI Listing |
Introduction: Dysphagia and cognitive impairment are prevalent in older individuals. This study aimed to understand the characteristics of dysphagia through fluoroscopy in older adults with mild cognitive impairment (MCI) and dementia.
Methods: A cross-sectional study was conducted at a memory clinic in a tertiary hospital in Mexico City.
Front Immunol
January 2025
Department of Otorhinolaryngology, Head and Neck surgery, University Hospital Leipzig, Leipzig, Germany.
Background: Adding pembrolizumab, an anti-PD-1 antibody approved for treatment of head and neck squamous cell carcinoma (HNSCC) to neoadjuvant (induction-) chemotherapy utilizing docetaxel and cisplatin (TP) followed by radiotherapy may improve outcome in larynx organ-preservation (LOP) that is investigated in the European Larynx-Organ preservation Study (ELOS). As biomarkers for response to TP and pembrolizumab +TP are missing but may include cytokines, this work aims on determining cytokines potentially linked to outcome as prognostic markers sufficient to predict and/or monitor response to successful LOP.
Methods: Collagenase IV digests were generated from 47 histopathological confirmed HNSCC tumor samples and seeded in 96-well plates containing pembrolizumab, docetaxel, cisplatin either solely or in binary or ternary combination.
Colomb Med (Cali)
January 2025
Phayao Hospital, Otolaryngology unit, Phayao, Thailand Phayao Hospital Otolaryngology unit Phayao Thailand.
Background: Managing foreign bodies in otorhinolaryngology requires appropriate treatment based on case severity.
Objective: To analyze the clinical characteristics associated with complicated cases of foreign bodies.
Methods: This study categorized patients with diagnosed foreign bodies into complicated and uncomplicated cases.
Sci Rep
January 2025
Cardiothoracic Surgery and Transplant Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
The choice between total thyroidectomy (TT) and subtotal thyroidectomy (STT) can affect postoperative complications and long-term outcomes in these patients. This study aimed to investigate postoperative complications and long-term outcomes in patients who underwent TT and STT. This retrospective study investigated 1.
View Article and Find Full Text PDFJ Voice
January 2025
Department of Otolaryngology Head and Neck Surgery, Drexel University College of Medicine, Philadelphia, PA. Electronic address:
Introduction: Voice abuse and misuse are the most common causes of benign vocal fold lesions (BVFL). Treatment may include a combination of voice therapy, singing sessions, or surgical resection. Otolaryngologists and speech language pathologists advocate for preoperative, as well as postoperative, voice therapy.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!