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Cardiac return assist blanket (CRAB) safely increases central venous pressure.
J Int Med Res
January 2025
Institute for Health Research, the University of Notre Dame Australia, Department of Research, Sir Charles Gairdner Hospital, Nedlands, Australia.
Objective: The cardiac return assist blanket (CRAB) has been designed to increase central venous pressure (CVP) to manage severe hypotension associated with anaphylaxis. This interventional study aimed to identify the relationship between CRAB pressure and CVP. CRAB pressure was also compared with the change in CVP associated with a straight leg raise (SLR), the Trendelenburg position, and 1 L of compound sodium lactate.
View Article and Find Full Text PDFCulprit allergen prevalence in polyreactive individuals reflects prescription trends: A tool for estimating comparative anaphylaxis risk using the example of neuromuscular blocking agents.
Anaesth Intensive Care
January 2025
Department of Anaesthesia, Sir Charles Gairdner Hospital, Nedlands, Australia.
Prescription-event monitoring (PEM) is the current gold standard for determining the risk of rare drug side-effects and comparing the risk between agents; however, spontaneous or prompted reporting schemes have low case-detection rates and exposure may be difficult to estimate. A novel method is described that allows a comparative adverse event rate between two drugs to be estimated-based on patterns of cross-reactivity-requiring only a sample of cases and no direct knowledge of drug exposure rates. Agreement was compared between the novel method and historical estimates of risk using PEM for comparative risk of rocuronium versus vecuronium anaphylaxis.
View Article and Find Full Text PDFGibberellin-Regulated Protein allergy may identify cypress pollen related fruit allergy with negative test to peach.
J Allergy Clin Immunol Pract
January 2025
Immunology Unit, Verona University Hospital, Verona, Italy. Electronic address:
If a cypress-sensitized patient experiences severe reactions to fruits-particularly with periorbital angioedema and cofactors present-consider testing for Pru p 7-specific IgE, even if initial tests, such as specific IgE to peach and SPT with peach extract, are negative.
View Article and Find Full Text PDFBackground: The evaluation and management of insect sting allergy is a complex core competency taught in Allergy and Immunology fellowship programs. It is unclear if current training on insect allergy is sufficient to meet the needs of the field, and what training barriers exist.
Objective: To investigate the extent of training on stinging insect allergy, and factors currently impacting stinging insect allergy clinical practice through a pilot needs-assessment survey.
Natural history of sesame allergy in pediatric patients: Insight from a retrospective analysis.
Pediatr Allergy Immunol
January 2025
Department of Pediatric Allergy, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Background: Sesame allergy (SA) is a growing concern because of its association with severe reactions and the limited knowledge of long-term outcomes.
Objective: This retrospective study aimed to identify the risk factors influencing persistent SA (PSA) in children to improve management and select suitable candidates for oral immunotherapy (OIT).
Methods: We analyzed the electronic medical records of 84 children with confirmed SA, as defined by consistent clinical reactions and immunoglobulin E (IgE)-mediated sensitization.
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