Long-term outcomes of pediatric ischemic stroke in adulthood.

J Child Neurol

Children's Stroke Program, Division of Neurology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada.

Published: June 2014

AI Article Synopsis

  • - The study analyzes how childhood strokes affect young adults' functioning and independence, including a group of 26 patients who had strokes when they were children, mostly assessing them at an average age of 21.5 years after about 10.8 years post-stroke.
  • - Results indicated that 37% of participants had normal outcomes, but 15% faced severe deficits; risk factors for worse outcomes included having arterial ischemic stroke and other medical conditions.
  • - Despite some deficits, most participants (77-84%) were able to live independently in areas like driving, work, and relationships, while mental health issues were noted in 25% of those studied, highlighting a need for further research in this area.

Article Abstract

This population-based study assesses the long-term impact of childhood stroke on function and independence in young adults. We undertook a cross-sectional outcome study of patients with arterial ischemic stroke and cerebral sinovenous thrombosis, beyond 18 years of age. We studied 26 patients; 21 arterial stroke, 5 cerebral sinovenous thrombosis, with 16 females. Mean age at assessment was 21.5 years, and mean follow-up time was 10.8 years. According to the modified Rankin Scale, final outcomes were 37% normal, 42% mild, 8% moderate, and 15% severe deficits. Risk factors for abnormal functional outcome included arterial ischemic stroke, presence of arteriopathy, and 1-year poststroke Pediatric Stroke Outcome Measure score ≥ 2 (P < .05). Most (77-84%) were independent in driving, relationships, and employment. Functional status at 1 year poststroke strongly predicts long-term outcome. Mental illness in one-quarter of young adults surviving childhood stroke represents an important direction for research.

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http://dx.doi.org/10.1177/0883073813484358DOI Listing

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