Background: In this study, we investigated the role of abdominal computed tomography (CT) in determining perforation findings and site in patients with gastrointestinal tract perforation.

Methods: Preoperative abdominal CT scans of 47 patients who had surgically proven gastrointestinal tract perforation between July 2007 and July 2010 were reviewed retrospectively. The presence of free air, leakage of contrast material, wall thickness, wall discontinuity, abscess, free fluid, and phlegmon were investigated for each patient. The site of perforation was estimated in light of these findings and compared with the surgical outcomes.

Results: Perforation sites were determined correctly in 85.7% of patients with gastroduodenal perforation, 85.7% of patients with small bowel perforation, 69.2% of patients with large bowel perforation, 100% of patients with rectum perforation, 90.9% of patients with appendix perforation, and 82.9% of all patients according to the abdominal CT findings. The most common CT finding in gastrointestinal tract perforation was free fluid, with a rate of 89.4%. The rates of other findings were as follows: free air 76.6%, segmental wall thickening 48.9%, wall discontinuity 25.5%, abscess 12.8%, and phlegmon 10.6%. Of 30 patients who received oral contrast, 7 (23.3%) had extraluminal contrast leakage.

Conclusion: CT is very effective in determining gastrointestinal tract perforation findings and the site of perforation.

Download full-text PDF

Source
http://dx.doi.org/10.5505/tjtes.2013.44538DOI Listing

Publication Analysis

Top Keywords

gastrointestinal tract
20
perforation
13
perforation findings
12
findings site
12
tract perforation
12
patients
10
role abdominal
8
abdominal computed
8
computed tomography
8
tomography determining
8

Similar Publications

Identification of Antigens Recognized by Murine Intestinal IgAs by a Gel-Independent Immunoproteomic Approach.

J Proteome Res

January 2025

Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza de Ramón y Cajal s/n, 28040 Madrid, Spain.

As part of the intestinal microbiota, can elicit a humoral response in the gastrointestinal tract (GIT) that is mainly directed toward hyphal antigens. This response has been implicated in controlling the invasive form of the fungus and maintaining the yeast as an innocuous commensal. However, the specific targets of this response are still unknown.

View Article and Find Full Text PDF

Decoding the role of ghrelin and its interactions with central signaling pathways in avian appetite regulation.

Vet Res Commun

January 2025

Department of Biology, Faculty of Basic Science, Central Tehran Branch, Islamic Azad University, Tehran, Iran.

Ghrelin, a peptide hormone primarily produced in the enteroendocrine cells of the gastrointestinal tract, plays a vital role in regulating food intake, and energy balance in avian species. This review examines the complex interactions between ghrelin and the central signaling pathways associated with hunger regulation in birds. In contrast to mammals, where ghrelin typically promotes feeding behavior, its effects in birds appear more nuanced, exhibiting anorexigenic properties under certain conditions.

View Article and Find Full Text PDF

Modification of spore shells into probiotic carriers: selective loading and colonic delivery of and effective therapy of inflammatory bowel disease.

Food Funct

January 2025

Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, 710072, Shaanxi, People's Republic of China.

Inflammatory bowel disease (IBD) is a chronic inflammation with a high incidence rate. Many probiotics, including (), have shown promise in IBD treatment. The therapeutic effects of most probiotics are greatly decided by the available live cells in the disease lesion, which is compromised as they pass through the gastric juice and intestinal tract, resulting in a loss of activity.

View Article and Find Full Text PDF

Aims: The gastrointestinal (GI) tract is composed of distinct sub-regions, which exhibit segment-specific differences in microbial colonization and (patho)physiological characteristics. Gut microbes can be collectively considered as an active endocrine organ. Microbes produce metabolites, which can be taken up by the host and can actively communicate with the immune cells in the gut lamina propria with consequences for cardiovascular health.

View Article and Find Full Text PDF

Correlation between IL-17 and inflammatory bowel disease.

Egypt J Immunol

January 2025

Department of Biology, Faculty of Science, University of Kufa, Najaf, Iraq.

Inflammatory bowel disease (IBD) is a protracted, persistent gastrointestinal disease that is distinguished by recurring, persistent inflammation of the digestive tract. IBD, including Crohn's disease and ulcerative colitis, is characterized by persistent inflammation due to immune dysregulation. Interleukin -17 (IL-17) contributes significantly to the pathophysiology of IBD, as highlighted in the context of the provided research.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!