Methotrexate (MTX) is a folic acid antagonist used at high-dose intravenously on 24 hours (24h) in the treatment of the acute lymphoblastic leukemia (ALL). To prevent potential toxicity, MTX is usually administered following the application of preventive measures. We report a case of an accidental shortening time for high dose MTX infusion and a literature review of accidental intoxications by the MTX. This case illustrates the importance of the respect of MTX high dose infusion time and the major role played by the therapeutic drug monitoring.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1684/abc.2013.0803 | DOI Listing |
Publication Analysis
Top Keywords
high dose
12
shortening time
8
time high
8
mtx
5
[accidental shortening
4
dose methotrexate
4
methotrexate infusion
4
infusion case
4
case report
4
report literature
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!