Background: Melioidosis, caused by Burkholderia pseudomallei, an important human pathogen in tropical regions, has protean multi-system clinical manifestations.
Methods: Case report and review of pertinent English-language literature.
Results: A 33-year-old male, who had been treated for pulmonary tuberculosis and multiple splenic abscesses four years previously, presented with a five-day history of acute-onset high-grade fever, abdominal pain and distension, and dyspnea. Laparotomy and drainage was done for paraumbilical abdominal wall abscess. Omentectomy was performed because the omentum was infarcted and studded with tubercles. Pus culture was positive for B. pseudomallei. The patient developed septic shock and succumbed on the fifth day after surgery.
Conclusion: This report emphasizes an unusual presentation of melioidosis and the diagnostic challenge posed by its clinical similarity to tuberculosis.
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http://dx.doi.org/10.1089/sur.2011.136 | DOI Listing |
Radiol Case Rep
December 2024
Department of Radiology, Faculty of Medicine, Thammasat University Hospital, Pathum Thani, Thailand.
Melioidosis, an infectious disease caused by Burkholderia pseudomallei, is prevalent in Southeast Asia and Northern Australia, presenting various clinical manifestations from asymptomatic to life-threatening infections. Although primarily affecting the lungs, intra-abdominal viscera, and musculoskeletal system, melioidosis can rarely involve the heart and mediastinum, which pose significant diagnostic and therapeutic challenges. Herein, we present the case of a 53-year-old male farmer who presented with persistent fever and chest pain, progressing to pericarditis and cardiac tamponade.
View Article and Find Full Text PDFHeliyon
May 2024
Department of Laboratory Medicine, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, People's Republic of China.
Background: Intra-abdominal abscesses are a frequent manifestations of melioidosis whereas pancreas is barely affected by this condition. Herein, by delving into the clinical manifestations, diagnostic processes, and the ultimate clinical outcome, we report a case of an unusual presentation of pancreatic melioidosis in a Chinese patient, aiming to shed light on a diagnosis that is not commonly associated with the pancreas.
Case Presentation: The patient, a 32-year-old male farmer, suffered from persistent burning pain in his upper abdomen, accompanied by nausea, vomiting, fever and other symptoms, presented to the clinic.
Int J Surg Case Rep
December 2021
University of the Philippines, Manila College of Medicine, Philippines; Makati Medical Center, Department of Surgery, Philippines.
Introduction: Melioidosis is a rare infectious tropical disease caused by Burkholderia pseudomallei (B. pseudomallei), an environmental saprophyte usually habitating on soils of Southeast Asian fields. Most of the reported cases present with pneumonia and intra-abdominal abscess.
View Article and Find Full Text PDFTravel Med Infect Dis
July 2019
Center for Experimental and Molecular Medicine and Melioidosis Expertise Center, Amsterdam UMC, Location Academic Medical Center (AMC), Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, the Netherlands; Division of Infectious Diseases, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:
Background: Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is an opportunistic infection across the tropics. Here, we provide a systematic overview of imported human cases in a non-endemic country over a 25-year period.
Methods: All 55 Dutch microbiology laboratories were contacted in order to identify all B.
Lancet Infect Dis
August 2019
Center for Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Division of Infectious Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, Netherlands.
Background: Melioidosis is an infectious disease caused by the environmental bacterium Burkholderia pseudomallei. It is often fatal, with a high prevalence in tropical areas. Clinical presentation can vary from abscess formation to pneumonia and sepsis.
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