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Technical feasibility and safety of transpedicular thoracic partial corpectomy using biportal endoscopic technique: a novel approach for separation surgery in spinal metastatic disease.
World Neurosurg
December 2024
Department of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States. Electronic address:
Quality of life outcomes in terminal cancer patients attending regional cancer centers in South Korea: protocol for a prospective cohort study.
BMC Cancer
December 2024
Department of Hemato-Oncology, Chungnam National University Hospital, Dajeon, Republic of Korea.
Introduction: Patients with cancer experience physical, mental, and social pain that affects themselves and their families. The increasing cancer incidence and advances in treatment have increased the number of cancer survivors in Korea, and there is an influx of patients in Seoul and other metropolitan areas, leading to shortages of continuous care and comprehensive life support facilities. Patients must travel long distances for treatment, which poses logistical and quality-of-life challenges.
View Article and Find Full Text PDFAssessing the prognostic impact of body composition phenotypes on surgical outcomes and survival in patients with spinal metastasis: a deep learning approach to preoperative CT analysis.
J Neurosurg Spine
December 2024
1Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts; and.
Objective: The prognostic significance of body composition phenotypes for survival in patients undergoing surgical intervention for spinal metastases has not yet been elucidated. This study aimed to elucidate the impact of body composition phenotypes on surgical outcomes and 5-year survival.
Methods: The records of patients treated surgically for spinal metastases between 2010 and 2020 were retrospectively evaluated.
Clinical Outcome of Single-Stage Posterior Decompression and Stabilisation for Spine Metastasis.
Malays Orthop J
November 2024
Department of Orthopaedics, Hospital Raja Permaisuri Bainun, Ipoh, Malaysia.
Introduction: Surgical treatment for indicated spinal metastases cases is an option to improve patients' outcomes. Local data in analysing the potential of patients' improvement after surgical treatment are limited. We intend to review the clinical outcomes of surgeries performed for cancer patients who were diagnosed with spinal metastases.
View Article and Find Full Text PDFIntrathecal pemetrexed for leptomeningeal metastases in a patient with ALK-rearranged lung adenocarcinoma: a case report.
Cancer Chemother Pharmacol
December 2024
Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford Cancer Institute, Stanford, USA.
Progressive leptomeningeal metastases (LM) are associated with intractable neurological symptoms and a poor prognosis, and effective treatment options are limited. Intrathecal (IT) pemetrexed has been shown to confer clinical benefit in lung adenocarcinoma, yet our understanding of the efficacy and safety of the treatment is limited. We report a patient with a long-standing history of leptomeningeal disease due to ALK-positive adenocarcinoma of the lung, previously controlled by increased doses of lorlatinib (125 mg/day).
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