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Posttraumatic Stress Disorder Is Associated With Endothelial Dysfunction in Women With HIV.

JACC Adv

January 2025

Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia, USA. Electronic address:

Background: HIV induced endothelial dysfunction (ED) contributes to cardiovascular disease (CVD) in women with HIV (WWH). Although psychosocial stress has been implicated in the development of CVD in HIV, its impact on ED in WWH remains unknown.

Objectives: The authors hypothesized that posttraumatic stress disorder (PTSD) and HIV interact to contribute to ED in WWH.

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Correlates of mental health of people living with HIV co-infected with SARS-CoV-2: findings from the COVIDHIV study in France.

Front Psychiatry

January 2025

Patient-Reported Outcomes Research (PROQOL), Health Economics Clinical Trial Unit (URC-ECO), Hotel-Dieu Hospital, AP- HP, Paris, France.

Background: The COVID-19 pandemic has severely affected vulnerable populations, especially individuals living with HIV/AIDS (PLWHA). The convergence of HIV/AIDS and COVID-19 presents unique challenges, exacerbating existing health concerns and magnifying the strain on individuals already grappling with compromised immune systems. This study aimed to investigate the mental well-being repercussions faced by PLWHA co-infected with SARS-CoV-2 in France.

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Objective: Natural variation in ovarian steroid hormones across the female lifespan contributes to an increased risk for depressive and posttraumatic stress disorder (PTSD) symptoms in women. However, minimal work has focused on understanding the impacts of reproductive aging on the brain and behavioral health of trauma-exposed women. This systematic review examines the bidirectional relationship between trauma-related psychopathology and reproductive aging.

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: Early interventions using trauma-focused cognitive behavioural therapy have the potential to alleviate post-traumatic stress symptoms in individuals who have experienced recent sexual assault. Specialized Sexual Assault Centers (SACs) in Norway offers psychosocial support, however, this support varies across SACs and its efficacy has not been researched. The Early Intervention after Rape (EIR) study is a multisite randomized controlled trial designed to assess the efficacy and effectiveness of training SAC nurses and social workers to deliver a modified version of prolonged exposure therapy shortly after rape.

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Addressing perinatal mood and anxiety disorders in obstetric settings: results of a cluster randomized controlled trial of two approaches.

Am J Obstet Gynecol MFM

January 2025

Department of Obstetrics and Gynecology, Psychiatry, Pediatrics, Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA (Simas); UMass Memorial Health Department of Obstetrics and Gynecology, Worcester, MA (Simas).

Article Synopsis
  • Mood and anxiety disorders affect one in five perinatal individuals, yet they are often not adequately treated due to various barriers in obstetric practices. To improve this situation, implementation assistance and an e-learning toolkit were developed for obstetric clinicians.
  • The main goal was to assess how these resources impacted the screening and treatment of mood and anxiety disorders compared to usual care by conducting a cluster randomized controlled trial across 13 obstetric practices in the U.S.
  • Results showed that there were no significant differences at baseline in mental health screening documentation among the groups, indicating a need for enhanced strategies in documenting and addressing these disorders effectively.
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