A 59-year-old white man was diagnosed with primary squamous cell carcinoma at the base of the tongue (clinical stage T4N3aM0). Cytogenetic analysis of the metaphase spreads obtained from primary cultures of the tumor tissue revealed a clonal abnormality with a 46,XY,t(2;6) (p23;q21),t(18;19)(q21;q13) karyotype.
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