Spinal injections are an important treatment option in the conservative management of many spinal disorders. A large number of imaging techniques are available to achieve a precise and safe needle placement in interventional procedures. Fluoroscopy-guided injections are safe, cost effective and available in most institutions. The following article presents an overview of common fluoroscopy-guided spinal injection therapy of the lumbar spine.
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http://dx.doi.org/10.1007/s00132-013-2078-0 | DOI Listing |
Eur J Nucl Med Mol Imaging
January 2025
CAS Key Laboratory of Molecular Imaging, Beijing Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, No.95 Zhongguancun East Road, Hai Dian District, Beijing, 100190, China.
Purpose: Precise tumor excision is important but challenging in breast-conserving surgery (BCS). Tumor-specific fluorescence imaging may be used for intraoperative tumor detection and, therefore, to guide precise tumor excision. The aims of this study are to develop a glucose transporter 1 (GLUT1)-targeted near-infrared fluorescence tracer and evaluate its accuracy for breast cancer detection using fresh surgical breast specimens.
View Article and Find Full Text PDFJ Colloid Interface Sci
April 2025
Department of Chemistry, Kay Lab of Bioorganic Phosphorus Chemistry and Chemical Biology of Ministry of Education, Beijing Key Laboratory for Analytical Methods and Instrumentation, Tsinghua University, 100084 Beijing, China. Electronic address:
The integration of reactive oxygen species (ROS) related photodynamic therapy (PDT) with the strategy of reshaping the tumor microenvironment (TME) has emerged as a potential approach for nanodiagnostic and therapeutic interventions. However, the therapeutic efficacy based on ROS treatments may be hindered by intracellular antioxidants such as glutathione (GSH) and tumor hypoxia. To address these challenges, a nanoplatform based on GSH-responsive multifunctional porphyrinic metal-organic framework (PCN-224@Au@MnO@HA, PAMH) was proposed.
View Article and Find Full Text PDFTheranostics
January 2025
Bionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.
Activatable multifunctional nanoparticles present considerable advantages in cancer treatment by integrating both diagnostic and therapeutic functionalities into a single platform. These nanoparticles can be precisely engineered to selectively target cancer cells, thereby reducing the risk of damage to healthy tissues. Once localized at the target site, they can be activated by external stimuli such as light, pH changes, or specific enzymes, enabling precise control over the release of therapeutic agents or the initiation of therapeutic effects.
View Article and Find Full Text PDFJ Am Acad Orthop Surg
December 2024
From the Department of Orthopedic Surgery, University of Montreal Health Center, Montreal, Quebec, Canada (Wang), the Department of Surgery, Montreal University, Montreal, Quebec, Canada (Wang), the Division of Orthopaedic Surgery, Dr. Georges-L-Dumont University Hospital Center, Moncton, New-Brunswick, Canada (Rizkallah), and University of Sherbrooke, Moncton, New-Brunswick, Canada (Rizkallah).
Atlantoaxial osteoarthritis (AAOA) is a clinical syndrome that consists of occipitocervical pain and cervical rotation limitation. Its clinical recognition is often deficient leading to misdiagnosis and suboptimal treatment. The incidence of AAOA varies from 5% in the sixth decade to as much as 18% in the ninth decade of life.
View Article and Find Full Text PDFSemin Musculoskelet Radiol
December 2024
Department of Radiology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
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