Experiments were conducted on donkeys to study the peculiarities of homeostasis in establishment of left ventricular bypass (LVB) by means of an artificial heart ventricle (AHV). Preliminary modelling of acute cardiac insufficiency makes the work of the AHV effective and ensures longer survival than that among intact animals. However, arterial hypertension and anemia accompanying prolonged work of the AHV and resulting from the interaction of the last named with the cardiovascular system sharply aggravate homeostasis and the course of LVB and lead to early death of the animals.
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