Aloe vera is used for vigor, wellness and medicinal purposes since rigvedic times. Health benefits of aloe vera include its application in wound healing, treating burns, minimizing frost bite damage, protection against skin damage from x-rays, lung cancer, intestinal problems, increasing high density lipoprotein (HDL), reducing low density lipoprotein (LDL), reducing blood sugar in diabetics, fighting acquired immune deficiency syndrome (AIDS), allergies and improving immune system. Phytochemistry of aloe vera gel has revealed the presence of more than 200 bioactive chemicals. Aloe vera gel is extracted from its leaves and appropriate processing techniques are needed for stabilization as well as preparation of the end products. The industries involved in processing of aloe vera need Government surveillance to ensure that the aloe vera products have beneficial bio-active chemicals as per claims of the manufacturers. Regulatory bodies also need to look into the safety and toxicological aspects of aloe vera products for food applications. The claims made for medicinal value of aloe products should be supported by authentic and approved clinical trial data. It is presumptive to mention that nutraceutical claims of aloe products made by the manufacturers are numerous. However, approved clinical evidences are available only for lowering LDL, increasing HDL, decreasing blood glucose level, treating genital herpes and psoriases.
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http://dx.doi.org/10.1007/s13197-011-0229-z | DOI Listing |
Int J Biol Macromol
January 2025
Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 1414614411, Iran. Electronic address:
Wound infection can prolong the healing process, leading to various complications. Although the use of antibiotics is common, it presents challenges such as poor pharmacokinetics. The prevalence of antibiotic resistance has further complicated wound management.
View Article and Find Full Text PDFMol Omics
January 2025
Departamento de Innovación Biomédica, Centro de Investigación Científica y de Educación Superior de Ensenada, Baja California (CICESE), Carretera Ensenada-Tijuana No. 3918, Zona Playitas, C.P. 22860, Ensenada, Baja California, Mexico.
Metabolic associated steatohepatitis characterized by lipid accumulation, inflammation and fibrosis, is a growing global health issue, contributing to severe liver-related mortality. With limited effective treatments available, there is an urgent need for novel therapeutic strategies. , rich in antioxidants, offers potential for combating steatohepatitis, but its cytotoxicity presents challenges.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Polymers and Biopolymers, Faculty of Chemistry, Rzeszów University of Technology, 6 Powstańców Warszawy Ave., Rzeszów, 35-959, Poland.
This study presents an investigation of the chemical composition of Aloe vera leaf tissue with a focus on the spatial distribution of compounds. The composition was studied using two mass spectrometry imaging techniques: silver-109 nanoparticles assisted laser desorption/ionization mass spectrometry imaging (AgNPs-LDI-MSI) and laser ablation-remote atmospheric pressure photoionization/chemical ionization mass spectrometry imaging (LARAPPI/CI-MSI) and the identification was aided by ultra-high-performance liquid chromatography and ultra-high-resolution mass spectrometry (UHPLC-UHRMS) analysis. The results showed an abundance of phenolic compounds with antioxidant, antimicrobial, and anti-inflammatory properties, making it a beneficial food additive and food packaging material.
View Article and Find Full Text PDFRSC Adv
January 2025
Centre for Advanced Materials and Devices (CAMD), Department of Chemistry, Faculty of Science, University of Colombo Colombo Sri Lanka
The global scarcity of irrigation-grade water poses severe concerns in the agricultural sector. Desalination techniques including reverse osmosis, electrodialysis, capacitive deionization, membrane filtration, and multi-stage flash are some dynamic solutions to mitigate this challenge. In this study, novel bio-filter materials were explored and developed for the application of membrane-based electrodialysis.
View Article and Find Full Text PDFPharm Nanotechnol
January 2025
Department of General Medicine, SRMC & RI, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai -600116, Tamil Nadu, India.
Aim: This study aimed to develop and evaluate lornoxicam (LXM) and thiocolchicoside (TCS) transferosomal transdermal patches.
Background: Oral administration of LXM and TCS can lead to gastric irritation, necessitating alternative delivery methods for pain and inflammation relief. Incorporating LXM & TCS into transferosomes within a transdermal patch offers a potential solution.
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