Syzygium cumini (S. cumini) (L.) Skeels (jambolan) is one of the widely used medicinal plants in the treatment of various diseases in particular diabetes. The present review has been primed to describe the existing data on the information on botany, phytochemical constituents, traditional uses and pharmacological actions of S. cumini (L.) Skeels (jambolan). Electronic database search was conducted with the search terms of Eugenia jambolana, S. cumini, jambolan, common plum and java plum. The plant has been viewed as an antidiabetic plant since it became commercially available several decades ago. During last four decades, numerous folk medicine and scientific reports on the antidiabetic effects of this plant have been cited in the literature. The plant is rich in compounds containing anthocyanins, glucoside, ellagic acid, isoquercetin, kaemferol and myrecetin. The seeds are claimed to contain alkaloid, jambosine, and glycoside jambolin or antimellin, which halts the diastatic conversion of starch into sugar. The vast number of literatures found in the database revealed that the extracts of different parts of jambolan showed significant pharmacological actions. We suggest that there is a need for further investigation to isolate active principles which confer the pharmacological action. Hence identification of such active compounds is useful for producing safer drugs in the treatment of various ailments including diabetes.
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http://dx.doi.org/10.1016/S2221-1691(12)60050-1 | DOI Listing |
Int J Biol Macromol
January 2025
P.G. Department of Biosciences, Sardar Patel University, Vallabh Vidyanagar 388 120, Gujarat, India.
Jamun (Syzygium cumini L. Skeels), a less recognized, underutilized, and highly perishable fruit is a delicacy of tropical regions. Soft pulp and thin exocarp make these small purple berries susceptible to mechanical injury and several postharvest diseases.
View Article and Find Full Text PDFNarra J
December 2024
Department of Pharmacology-Clinical Pharmacy, School of Pharmacy, Institut Teknologi Bandung, Bandung, Indonesia.
and are mostly cultivated in tropical climates for culinary and perfumery purposes, yet their potential medicinal properties remain underreported. The aim of this study was to examine the antioxidant and immunomodulatory activities of ethanol extracts from (EESC) and (EEPC). Reflux extraction was carried out using 96% ethanol on the collected plant specimens to produce EESC and EEPC.
View Article and Find Full Text PDFPharmaceutics
October 2024
Laboratory of Preclinical Research of Natural Products, Paranaense University (UNIPAR), Umuarama 87502-210, Brazil.
Background/objectives: Considering the antioxidant and antimicrobial properties attributed to compounds in extract, this research aimed to advance postoperative therapeutic innovations. Specifically, the study assessed the physicochemical properties of a film-forming solution (FFS) incorporated with , evaluating its therapeutic potential for postoperative applications.
Methods: The extract was meticulously characterized to determine its chemical composition, with particular emphasis on the concentration of phenolic compounds.
Heliyon
September 2024
Postgraduate Program in Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte (UFRN), 59078-900, Natal, Brazil.
Jambolan ( L.) is an underutilized fruit rich in bioactive phenolic compounds, specially anthocyanins, but the low stability of these substances and interaction with other compounds in the food matrix limit their application as food additives; nanoencapsulation is the best strategy to overcome these limitations. This study aimed to nanoencapsulate a phenolic-rich jambolan extract using whey proteins and pectin by nanoprecipitation in different antisolvent compositions.
View Article and Find Full Text PDFJ Ethnopharmacol
January 2025
Symbiosis School of Biological Sciences (SSBS), Symbiosis International (Deemed University) (SIU), Lavale, Pune, Maharashtra State, India. Electronic address:
Ethnopharmacological Prevalence: Hyperglycemia in diabetes increases the generation of advanced glycation end products (AGEs) through non-enzymatic reactions. The interaction between AGEs and their receptors (RAGE) leads to oxidative and inflammatory stress, which plays a pivotal role in developing diabetic nephropathy. Syzygium cumini (SC) L.
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