Objective: To evaluate the antiarthritic activity of Ajuga bracteosa using albino rats.
Methods: The antiarthritic activity of 70% ethanolic extract of Ajuga bracteosa (EEAB) was evaluated against turpentine oil- and formaldehyde- induced acute non immunological and complete freund's adjuvant (CFA)-induced chronic immunological arthritis in albino rats.
Results: EEAB showed a significant (P<0.05) and dose dependent inhibitory effect against acute and chronic models of arthritis. EEAB exhibited better antiarthritic activity than the standard aspirin.
Conclusions: EEAB exhibits a significant and promising antiarthritic activity against acute and chronic arthritis and supports the traditional use of Ajuga bracteosa for rheumatism and other inflammatory diseases.
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http://dx.doi.org/10.1016/S2221-1691(12)60039-2 | DOI Listing |
Heliyon
July 2024
Department of Pharmaceutical Sciences, School of Applied Science and Technology, University of Kashmir, Srinagar, 190006, Jammu and Kashmir, India.
() has tremendous medicinal value with long-established disease curing potential. The present study aimed to assess the hepatoprotective potential of extracts in paracetamol-induced hepatotoxicity in mice. Group I (normal control) were treated with saline 1 ml/kg BW orally for 7 days while Group II (toxicant control) received saline 1 ml/kg BW for 6 days and Paracetamol (1000 mg/kg BW) on day7of the treatment.
View Article and Find Full Text PDFMicrosc Res Tech
August 2024
Department of Biotechnology, Mirpur University of Science and Technology, Mirpur, Pakistan.
In this study, gold nanoparticles (AuNPs) were bioreduced from Ajuga bracteosa, a medicinal herb known for its therapeutic properties against various diseases. Different fractions of the plant extract were used, including the methanolic fraction (ABMF), the n-hexane fraction (ABHF), the chloroform fraction (ABCF), and the aqueous extract for AuNPs synthesis. The characterization of AuNPs was performed using UV-Vis spectrophotometry, FT-IR, XRD, EDX, and TEM.
View Article and Find Full Text PDFFront Chem
January 2024
Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Front Plant Sci
October 2023
College of Pharmaceutical Science, Dali University, Dali, China.
Introduction: The potential contamination of herbal medicinal products poses a significant concern for consumer health. Given the limited availability of genetic information concerning Ajuga species, it becomes imperative to incorporate supplementary molecular markers to enhance and ensure accurate species identification.
Methods: In this study, the chloroplast (cp) genomes of seven species of the genus Ajuag were sequenced, de novo assembled and characterized.
PLoS One
August 2023
Department of Bioscience, COMSATS University, Islamabad, Pakistan.
The current study is designed to synthesize gold nanoparticles using Ajuga bracteosa extract, which is a highly known medicinal herb found in the northern Himalayas. The synthesized gold nanoparticles were initially characterized by UV-Vis spectrophotometer, SEM, FTIR, pXRD, and, GC-MS. Antibacterial efficacy of A.
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