Antiarthritic effects of Ajuga bracteosa Wall ex Benth. in acute and chronic models of arthritis in albino rats.

Asian Pac J Trop Biomed

Department of Pharmaceutical Sciences, Assam University, Silchar-788 011, Assam, India.

Published: March 2012

Objective: To evaluate the antiarthritic activity of Ajuga bracteosa using albino rats.

Methods: The antiarthritic activity of 70% ethanolic extract of Ajuga bracteosa (EEAB) was evaluated against turpentine oil- and formaldehyde- induced acute non immunological and complete freund's adjuvant (CFA)-induced chronic immunological arthritis in albino rats.

Results: EEAB showed a significant (P<0.05) and dose dependent inhibitory effect against acute and chronic models of arthritis. EEAB exhibited better antiarthritic activity than the standard aspirin.

Conclusions: EEAB exhibits a significant and promising antiarthritic activity against acute and chronic arthritis and supports the traditional use of Ajuga bracteosa for rheumatism and other inflammatory diseases.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609278PMC
http://dx.doi.org/10.1016/S2221-1691(12)60039-2DOI Listing

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