AI Article Synopsis
- The study aimed to assess the safety and feasibility of a new laparoscopic technique for segmental colectomy and anastomosis in rats.
- Thirty rats were divided into three groups: one underwent laparoscopic surgery at low pressure, another at high pressure, and the control group had open surgery, with post-op evaluations on day seven.
- Results showed no major complications in any group, with one case of leakage in the low-pressure group, and overall, the technique was deemed safe and effective.
Article Abstract
Purpose: To evaluate the feasibility and safety of a new technique for laparoscopic segmental colectomy and primary anastomosis in the left colon of rats.
Methods: Thirty rats were randomly assigned to three groups of ten animals each. All animals underwent segmental resection of the left colon and end-to-end anastomosis. In Group I, the animals underwent laparoscopic surgery with carbon dioxide pneumoperitoneum at a pressure of 5 mmHg. In Group II, the animals underwent pneumoperitoneum with carbon dioxide at a pressure of 12 mmHg. In Group III, the control group, the animals underwent open surgery. All animals were reopened on the 7th postoperative day and were evaluated for peritonitis, abscesses, anastomotic dehiscence and bowel obstruction, and the anastomosis bursting pressure was measured.
Results: No obstructions, peritonitis or abscesses were found in any of the animals. An animal in Group I exhibited a blocked anastomosis leakage. The average anastomosis bursting pressure in the 30 animals was 187.02 ± 68.35 mmHg. There was no significant difference in the anastomosis bursting pressure among the groups (p = 0.503)
Conclusion: The laparoscopic experimental model was feasible and safe for segmental colectomy and anastomosis of the left colon in rats.
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| http://dx.doi.org/10.1590/s0102-86502013000400002 | DOI Listing |
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