Classification of a smooth muscle neoplasm as benign or malignant is straightforward. Morphologic and biologic diversity makes smooth muscle neoplasia a diagnostic dilemma for pathologists but fascinating area of study. We report three cases of unusual types of smooth muscle tumors of uterine corpus: 1) highly cellular leiomyoma; 2) cotyledonoid dissecting leiomyoma (CDL) and 3) poorly differentiated leiomyosarcoma. Diagnostic pathology of the uterine smooth muscle tumors hides pitfalls. Some of the tumor type requires ancillary techniques to establish correct diagnosis. In case of CDL only gross and/or histopathologic features can clarify the question. There are number of cases, were the complex methods must be utilized.
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