Characterising the mechanical properties of human facial skin is a challenging but important endeavour with applications in biomedicine, surgery simulation, forensics, and animation. Many existing computer models of the face are not based on in vivo facial skin deformation data but rather on experiments using in vitro facial skin or other soft tissues. The facial skin of five volunteers was subjected to a rich set of deformations using a micro-robotic device. The force-displacement response was recorded for each deformation. All volunteers' facial skin exhibited a non-linear, anisotropic, and viscoelastic force-displacement response. We propose a finite element model that simulated the experimental deformations with error-of-fits ranging from 11% to 23%. The skin was represented by an Ogden strain energy function and a quasi-linear viscoelastic law. From non-linear optimisation procedures, we determined material parameters and in vivo pre-stresses for the central cheek area of five volunteers and five other facial points on one volunteer. Pre-stresses ranged from 15.9kPa to 89.4kPa.
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http://dx.doi.org/10.1016/j.jmbbm.2013.03.004 | DOI Listing |
Aesthetic Plast Surg
January 2025
Department of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, No.1, Shuaifuyuan, Dongcheng District, Beijing, China.
Background: Perioral rejuvenation is challenging due to the lack of spatial anatomical understanding of the labiomandibular fold (LMF). The LMF's formation mechanism remains underexplored due to intricate relationships between musculature and subcutaneous structures. This study aimed to clarify the three-dimensional structures of the LMF using micro-computed tomography and histology.
View Article and Find Full Text PDFJ Dermatolog Treat
December 2025
Department of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Keloid tissue represents an abnormal proliferation of fibroblasts, typically resulting from skin injury. These lesions can lead to significant physiological dysfunction and aesthetic concerns, particularly when located on the face. Traditional treatments, such as intralesional injections, laser therapy, and surgical excision, have shown limited efficacy and are associated with high recurrence rates.
View Article and Find Full Text PDFJ Craniofac Surg
January 2025
Department of Cosmetic Injection Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College.
Hyaluronic acid filler treatment is increasingly prevalent in the realm of plastic surgery, serving to correct a range of facial changes resulting from aging. Nevertheless, with its expanded application, an uptick in complications has been observed. This article reported a 30-year-old female patient who received chin hyaluronic acid filler treatment 5 years ago started experiencing atrophy and progressive deterioration at the injection site a year ago.
View Article and Find Full Text PDFJ Dermatol
January 2025
Department of Dermatology, Tokyo Women's Medical University Adachi Medical Center, Tokyo, Japan.
Reactive B-cell rich lymphoid proliferation (rB-LP), once called pseudolymphoma, is a benign lymphoproliferative disorder, which is histologically characterized by dense dermal infiltrate forming reactive germinal centers with tingible body macrophages. The disease frequently involves the face, scalp, and ear lobes. Treatment includes topical or intralesional steroids, surgical resection, ultraviolet therapy, laser treatment, and radiation therapy.
View Article and Find Full Text PDFActa Dermatovenerol Croat
November 2024
Constantin A. Dasanu MD, PhD, Lucy Curci Cancer Center, Eisenhower Health, 39000 Bob Hope Dr, Rancho Mirage, CA 92270 , USA;
Erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), is currently used in the therapy of several solid malignancies. This agent has been associated with several dermatological side-effects, the most common being papulo-pustular acneiform rash. Herein we describe a unique skin effect in a patient treated with erlotinib for non-small cell lung cancer.
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