Background: Canine distemper virus (CDV) infects a variety of carnivores, including wild and domestic Canidae. In this study, we sequenced and phylogenetic analyses of the hemagglutinin (H) genes from eight canine distemper virus (CDV) isolates obtained from seven raccoon dogs (Nyctereutes procyonoides) and a giant panda (Ailuropoda melanoleuca) in China.
Results: Phylogenetic analysis of the partial hemagglutinin gene sequences showed close clustering for geographic lineages, clearly distinct from vaccine strains and other wild-type foreign CDV strains, all the CDV strains were characterized as Asia-1 genotype and were highly similar to each other (91.5-99.8% nt and 94.4-99.8% aa). The giant panda and raccoon dogs all were 549Y on the HA protein in this study, irrespective of the host species.
Conclusions: These findings enhance our knowledge of the genetic characteristics of Chinese CDV isolates, and may facilitate the development of effective strategies for monitoring and controlling CDV for wild canids and non-canids in China.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636003 | PMC |
| http://dx.doi.org/10.1186/1743-422X-10-109 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Seroprevalence of canine distemper virus antibodies in free-roaming dogs in Cambodia.
Vet J
December 2024
Queensland Alliance for One Health Sciences, School of Veterinary Sciences, The University of Queensland, Gatton, Australia.
Canine distemper virus (CDV) can infect a wide range of mammalian carnivores and can cause severe illness and death. Domestic dogs may be an important source of this virus for endangered wild carnivores. The objective of this study was to establish the presence of CDV in rural areas of Cambodia bordering three established protected habitats, and to determine the seroprevalence of CDV in free-roaming dogs inhabiting these areas.
View Article and Find Full Text PDFExpression and characterization of canine distemper virus hemagglutinin protein in suspension mammalian cells.
J Virol Methods
December 2024
Department of Viral Infectious Diseases of Special Animals, Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, China; Jilin Provincial Key Laboratory of Special Economic Animal Molecular Biology, Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, China. Electronic address:
Hundreds of millions of the domestic dogs worldwide are routinely inoculated with the modified live vaccines for canine distemper virus (CDV) every year. However, the corresponding serological diagnostic and detections are always lacking, thus, there is an urgent demand to establish its unique diagnostic technologies to produce high-quality antigenic biomolecules. In the present study, the ectodomain (et) of CDV hemagglutinin (H) protein was firstly expressed in a soluble and secreted forms by an Expi293F transient transfection system based on its antigenic secondary structure analysis.
View Article and Find Full Text PDFMolecular detection and quantification of canine parvovirus 2 using a fast and sensitive SYBR green-based quantitative polymerase chain reaction assay in dogs affected with gastroenteritis.
Vet World
October 2024
Facultad de Ciencias de la Salud, Carrera de Medicina Veterinaria, Universidad de Las Américas (UDLA), Quito, Ecuador, Antigua Vía a Nayón S/N, Quito EC 170124, Ecuador.
Background And Aim: Viral gastroenteritis in canines is primarily caused by the canine parvovirus 2 (CPV-2). Infections by this virus can cause severe consequences in dogs, such as fever, vomiting, diarrhea, septicemia, systemic inflammation, and immunosuppression. Therefore, the mortality rate of persistent infections caused by this virus is significantly high.
View Article and Find Full Text PDFEpidemiological Survey of Canine Distemper Virus Infection: Exploring the Link Between Virus Spread and Invasive Raccoon (Procyon lotor) Population Growth in Hokkaido, Japan.
Integr Zool
December 2024
Laboratory of Wildlife Biology and Medicine, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Article Synopsis
- Invasive raccoons in Hokkaido, Japan, are potential carriers of the canine distemper virus, with a study analyzing 611 serum samples revealing higher infection rates in 2007, 2021, and 2022 compared to 2008-2012, indicating outbreak occurrences during those years.
- Logistic regression showed that raccoon population density and environmental factors, like residential area ratios, were linked to seropositivity rates, particularly highlighting changes over the years from forest to residential areas.
- Ongoing monitoring and improved raccoon control efforts are crucial to prevent disease spread to native wildlife like raccoon dogs and foxes, as well as to protect domestic dogs from health risks.
Risk of canine distemper virus vaccination of domestic dogs in giant panda habitat to giant pandas.
Sci Rep
November 2024
College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Article Synopsis
- The giant panda, an emblem of biodiversity conservation, is threatened by the canine distemper virus (CDV), making the vaccination of domestic dogs in their habitats essential.
- A study of 69 domestic dogs showed that vaccinated dogs can shed the virus starting nine days after vaccination, with unvaccinated dogs also at risk of increased antibody levels and viral shedding.
- To protect giant pandas, it’s recommended that vaccinated dogs have restricted activity for at least three weeks post-vaccination, alongside collaboration among local authorities and community members for better management of domestic dog vaccinations.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!