The time-space organization of biological systems, cell systems in particular, is one of the most important problems of current theoretical biology having medical implications. The presented view of the general structure of the temporal organization of biosystems and their development in the course of life evolution interprets the temporal organization of a living system as a complex of regular changes in time, the biological rhythms included, its structures and functions which are interactive and show relationships with cyclic alterations of environmental conditions. A special organization is composed of a group of different structures and related functions which are arranged according to a certain pattern in the space occupied by the biological system and interact with each other. The experimental evidence obtained in studies of the proliferative and metabolic systems of the liver, testify to the existence of a general time-space organization in the cell systems. This organization represents an entity formed by the cellular temporal and special organizations and maintained by relationships and interactions between them.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
The '5 Moments for Hand Hygiene': casting a critical eye on the implications for practice.
Br J Nurs
December 2024
Senior Lecturer in Nursing. Division of Nursing, Midwifery & Social Work, University of Manchester.
The '5 Moments' approach is a time-space framework that delineates when hand hygiene should be performed and provides a resource for educators and auditors. It has become the dominant paradigm for organisations, practice, policy, and research in relation to hand hygiene. It is a concept that adopts the 'precautionary principle' that if the relative risk of a specific care task is unknown, a safe system must be to treat them on an equal level.
View Article and Find Full Text PDFEnabling pharmacist prescribing: Lessons learned in Nova Scotia using behaviour change theory.
Can Pharm J (Ott)
November 2024
College of Pharmacy, Dalhousie University, Halifax, Nova Scotia.
Background: The COVID-19 pandemic alongside increased patient demand, enablement of scope, and government funding has accelerated the need and demand for pharmacist prescribing in Nova Scotia.
Methods: A sequential explanatory mixed-methods study was undertaken to understand barriers and facilitators to pharmacist prescribing in Nova Scotia, Canada. This consisted of: 1) a cross-sectional survey and 2) semistructured, qualitative interviews with pharmacists practising in the community.
Reconstructed influenza A/H3N2 infection histories reveal variation in incidence and antibody dynamics over the life course.
PLoS Biol
November 2024
MRC Centre for Global Infectious Disease Analysis, Imperial College London, London, United Kingdom.
Humans experience many influenza infections over their lives, resulting in complex and varied immunological histories. Although experimental and quantitative analyses have improved our understanding of the immunological processes defining an individual's antibody repertoire, how these within-host processes are linked to population-level influenza epidemiology in humans remains unclear. Here, we used a multilevel mathematical model to jointly infer antibody dynamics and individual-level lifetime influenza A/H3N2 infection histories for 1,130 individuals in Guangzhou, China, using 67,683 haemagglutination inhibition (HI) assay measurements against 20 A/H3N2 strains from repeat serum samples collected between 2009 and 2015.
View Article and Find Full Text PDFInterdisciplinary Operating Room Ergonomics Needs and Priorities: A Survey of Operating Room Staff.
Ann Surg
November 2024
Evaluative Clinical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Objective: To examine perceived OR ergonomics facilitators and barriers, with a focus on the interdisciplinary team.
Summary Background Data: Poor ergonomics causes musculoskeletal injuries affecting all operating room (OR) staff with repercussions on patient care, outcomes, and sustainability. Lack of ergonomic awareness and education are risk factors.
The influence of event similarity on the detailed recall of autobiographical memories.
Memory
September 2024
Department of Psychology, University of Toronto, Toronto, Canada.
Memories for life events are thought to be organised based on their relationships with one another, affecting the order in which events are recalled such that similar events tend to be recalled together. However, less is known about how detailed recall for a given event is affected by its associations to other events. Here, we used a cued autobiographical memory recall task where participants verbally recalled events corresponding to personal photographs.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!