Isoxazoline insecticides have been shown to be potent blockers of insect GABA receptors with excellent activity on a broad pest range, including Lepidoptera and Hemiptera. Herein we report on the synthesis, biological activity and mode-of-action for a class of 4-heterocyclic aryl isoxazoline insecticides.
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Efficacy and utility of isocycloseram a novel isoxazoline insecticide against urban pests and public health disease vectors.
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Syngenta AG, Basel, Switzerland.
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J Agric Food Chem
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College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi, China.
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October 2024
Key Laboratory of Integrated Pest Management on Crops in East China, Ministry of Agriculture and Rural Affairs/Key Laboratory of Integrated Management of Crop Diseases and Pests, Education of Ministry, College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, P. R. China.
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State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, P. R. China.
Article Synopsis
- * A series of new isoxazoline compounds with acylhydrazine were created and tested for insecticidal activity, with one compound showing superior effectiveness compared to commercial options.
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State Key Laboratory of Green Pesticide, Key Laboratory of Natural Pesticide and Chemical Biology, Ministry of Education, College of Plant Protection, South China Agricultural University, Guangzhou, Guangdong 510642, People's Republic of China. Electronic address:
Isoxazoline insecticides have shown broad-spectrum insecticidal activity against a variety of insect pests. However, the high toxicity of isoxazoline compounds towards honeybees restricts their application in crop protection. To mitigate this issue, a series of isoxazoline derivatives containing 2-phenyloxazoline were designed and synthesized.
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