Prednisolone is a steroid belonging to the corticosteroid group. The results obtained in the application of the 2008 and 2009 Italian Residue Control Plans show the frequent detection of prednisolone traces in cow's urine. Since most of the positive samples were detected at the slaughterhouse, the researchers hypothesised that, together with an increase of cortisol concentration, traces of prednisolone could be produced endogenously during stressful situations due to transport and handling before slaughter. In the present trial, 52 lactating cows housed in seven different farms in Lombardy, Italy, were studied. Urine samples were collected at the farm (after urethral catheterisation) and immediately after slaughter (from urinary bladder) together with 40 adrenal gland samples belonging to the same animals. All the samples were analysed for the determination of prednisolone and cortisol by LC/MS(n). The results demonstrated that prednisolone can be endogenously produced in dairy cows and, furthermore, its endogenous presence in bovine urine seems to be strongly related to a state of stress in the animals (at the farm and at the slaughterhouse). The data from adrenal glands do not, however, clarify if the endogenous production occurs, partially or totally, in this organ.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/19440049.2013.781273 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparison of postoperative biochemical indicators and surgical result between partial adrenalectomy and total adrenalectomy: a systematic review and meta-analysis.
Gland Surg
December 2024
Department of Urology, Surgical Ward One, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Background: The selection and extent of application for both total adrenalectomy (TA) and partial adrenalectomy (PA) within this surgical approach continue to be matters of debate. This paper compares the postoperative efficacy and functional indicators of PA and TA to provide comprehensive insights for clinicians to consider the best surgical treatment options.
Methods: Systematic review on PubMed, Embase, Cochrane Library, Web of Science, and China National Knowledge Infrastructure (CNKI) was conducted.
Myelolipoma of the adrenal gland is a rare, benign, non-functioning tumor characterized by the presence of adipose tissue and bone marrow elements. We present the case of a 48-year-old woman with intermittent left flank pain and an incidental finding of an adrenal tumor on computed tomography. The patient underwent laparoscopic tumor resection due to the large size of the tumor.
View Article and Find Full Text PDF[Addison's disease: looking to the past and the future].
Rev Med Liege
January 2025
Service d'Endocrinologie, CHU Liège, Belgique.
In 1849, Thomas Addison discovered alterations in the adrenal glands at autopsy of three patients who had died with idiopathic anemia. Struck by Addison's work, Charles-Edouard Brown-Séquard demonstrated in 1851 that bilateral adrenalectomy in dogs was fatal. It was not until 1950 that the discovery of the hormones of the adrenal cortex, their structure and their biological effects allowed Kendall, Reichstein and Hench to win the Nobel Prize in Physiology or Medicine.
View Article and Find Full Text PDFCharacterization of adrenal glands on computed tomography with a 3D V-Net-based model.
Insights Imaging
January 2025
Department of Radiology, Peking University First Hospital, Beijing, 100034, China.
Objectives: To evaluate the performance of a 3D V-Net-based segmentation model of adrenal lesions in characterizing adrenal glands as normal or abnormal.
Methods: A total of 1086 CT image series with focal adrenal lesions were retrospectively collected, annotated, and used for the training of the adrenal lesion segmentation model. The dice similarity coefficient (DSC) of the test set was used to evaluate the segmentation performance.
Erlotinib-induced Perioral Lesions Resembling Scleroderma.
Acta Dermatovenerol Croat
November 2024
Constantin A. Dasanu MD, PhD, Lucy Curci Cancer Center, Eisenhower Health, 39000 Bob Hope Dr, Rancho Mirage, CA 92270 , USA;
Erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), is currently used in the therapy of several solid malignancies. This agent has been associated with several dermatological side-effects, the most common being papulo-pustular acneiform rash. Herein we describe a unique skin effect in a patient treated with erlotinib for non-small cell lung cancer.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!