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Objective: To investigate whether the live birth rate following in vitro fertilization (IVF) is affected by thyroid autoimmunity (TAI) and/or subclinical hypothyroidism in subfertile women.
Design And Setting: Retrospective study in a university infertility clinic.
Patients: A total of 627 women without past or current history of thyroid disorder undergoing their first IVF cycle.
Intervention: Pre-IVF archived blood serum samples were tested for TAI and thyroid function tests.
Main Outcome Measure: Live birth rate.
Results: The clinical pregnancy rate, live birth rate and miscarriage rate were similar among women with or without TAI and/or subclinical hypothyroidism using a TSH threshold 4·5 mIU/l. Thyroid autoantibody level did not affect these IVF outcomes.
Conclusion: The live birth rate and miscarriage rate of women with TAI and/or subclinical hypothyroidism following IVF were not impaired.
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| http://dx.doi.org/10.1111/cen.12220 | DOI Listing |
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