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[Rat bite fever in children].
Ned Tijdschr Geneeskd
May 2024
Canisius-Wilhelmina Ziekenhuis, Nijmegen. Afd. Kindergeneeskunde.
Background: Worldwide, disease in children due to exposure to rats is increasing, also in the Netherlands. Not only the generally known pathogen Leptospira should be considered, also , , Lymphocytic choriomeningitis virus, Hantavirus, and are also known rat-associated zoonosis.
Case Description: An 12-year-old boy visited the pediatrician with fever, headache and nausea, followed by generalized erythema and arthritis.
In silico design and evaluation of a multiepitope vaccine targeting the nucleoprotein of Puumala orthohantavirus.
Proteins
October 2024
Centre for Inflammation, Centenary Institute and University of Technology Sydney, Faculty of Science, School of Life Sciences, Sydney, New South Wales, Australia.
The Puumala orthohantavirus is present in the body of the bank vole (Myodes glareolus). Humans infected with this virus may develop hemorrhagic fever accompanying renal syndrome. In addition, the infection may further lead to the failure of an immune system completely.
View Article and Find Full Text PDFA cluster of 3 persons in Germany experienced hantavirus disease with renal insufficiency. Reverse transcription PCR-based genotyping revealed infection by Seoul hantavirus transmitted from pet rats. Seoul virus could be responsible for disease clusters in Europe, and infected pet rats should be considered a health threat.
View Article and Find Full Text PDFFDG PET/CT in Hantavirus Hemorrhagic Fever With Renal Syndrome.
Clin Nucl Med
December 2023
Internal Medicine, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University Medical School and Hospital, Jeonju, Jeonbuk, Republic of Korea.
A 58-year-old man with fever, myalgia, and dysuria was admitted to the hospital. Because of prolonged fever, FDG PET/CT was performed. Surprisingly, bilateral kidneys were rapidly enlarged for 5 days with the renal parenchyma showing intense hypermetabolism.
View Article and Find Full Text PDFPet Rats as the Likely Reservoir for Human Seoul Orthohantavirus Infection.
Viruses
February 2023
Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald, Germany.
Seoul orthohantavirus (SEOV) is a rat-associated zoonotic pathogen with an almost worldwide distribution. In 2019, the first autochthonous human case of SEOV-induced hemorrhagic fever with renal syndrome was reported in Germany, and a pet rat was identified as the source of the zoonotic infection. To further investigate the SEOV reservoir, additional rats from the patient and another owner, all of which were purchased from the same vendor, were tested.
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