Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1590/0037-8682201200212013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Characterization of Biopolymer Hydrogels Prepared with Water Exposed to Indirect Plasma Treatment.
Int J Mol Sci
December 2024
Department of Functional Food Products Development, The Faculty of Biotechnology and Food Science, Wroclaw University of Environmental and Life Sciences, Chelmonskiego 37/41, 51-630 Wroclaw, Poland.
This study aimed to evaluate the influence of indirect-plasma-treated water (IPTW) in the preparation of hydrogels. Three commonly used natural, biodegradable polymers with the ability to form gels were selected: gelatin, carrageenan, and sodium alginate. The pH, gelling temperature, texture profile, swelling degree, and color of hydrogels were evaluated, and the polymers were subjected to Fourier-transform infrared (FTIR) spectroscopy.
View Article and Find Full Text PDFClinical Profile and Management of Wolf-Parkinson White Syndrome and Asymptomatic Pre-Excitation Carriers in Africa: A Multicenter Pan African Registry From 17 Countries.
J Cardiovasc Electrophysiol
January 2025
Douala Gyneco-obstetric and Pediatric Hospital/University of Douala, Douala, Cameroon.
Article Synopsis
- The study explores the management and diagnosis of Wolf-Parkinson White Syndrome (WPW) and asymptomatic pre-excitation in Africa, highlighting a lack of data in the region.
- Conducted in 20 centers across 17 African countries, the research involved 541 participants and focused on symptomatology, treatment approaches, and the impact of local health dynamics on care.
- Results indicated that a vast majority were diagnosed with WPW, with significant regional differences in treatment options and effectiveness, showing that Northern and Southern Africa have more advanced practices compared to other areas.
Lenvatinib plus immunotherapy versus lenvatinib monotherapy in lenvatinib-insensitive patients with unresectable hepatocellular carcinoma: a retrospective study.
Invest New Drugs
January 2025
Interventional Radiology Department, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.
Purpose: The combination therapy of lenvatinib and immunotherapy as first-line treatment remains controversial in unresectable hepatocellular carcinoma (uHCC). This research aimed to compare the efficacy and safety of lenvatinib monotherapy (L) and combination therapy of lenvatinib and immune checkpoint inhibitor (LI) in lenvatinib-insensitive patients with uHCC.
Methods: Two hundred fifty-five uHCC patients were enrolled in this study.
Use of Clinical Trial Characteristics to Estimate Costs of New Drug Development.
JAMA Netw Open
January 2025
RAND, Santa Monica, California.
Article Synopsis
- Estimates indicate significant variation in R&D costs, with 20 large firms comprising 80.8% of patient-months and showing lower costs per patient-month compared to smaller firms.
- A novel methodology was used to analyze R&D costs per drug, focusing on discrete units of activity related to clinical trials and using data from 268 US publicly traded drug developers.
- The study found that R&D costs per new drug averaged around $1.31 billion, with a lower median cost of $708 million, highlighting a skewed distribution of expenses related to drug development.
Aetiology, diagnosis and treatment of thalassemia-associated osteoporosis of the adult.
J Endocrinol Invest
January 2025
Section of Endocrinology, Geriatrics and Internal Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Aim: This review aims to overview factors contributing to TAO development and addresses the targeted diagnostic work-up and treatment management in adult thalassemic patients.
Results: Osteoporosis management in Thalassemia is challenging because several factors contributing to its pathogenesis should be considered and controlled starting from child- hood. A multidisciplinary approach is crucial.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!