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Amount of colicin release in Escherichia coli is regulated by lysis gene expression of the colicin E2 operon.
PLoS One
January 2016
Center for NanoScience, Faculty of Physics, Ludwig-Maximilians-Universität München, Geschwister-Scholl-Platz 1, Munich, Germany.
The production of bacteriocins in response to worsening environmental conditions is one means of bacteria to outcompete other microorganisms. Colicins, one class of bacteriocins in Escherichia coli, are effective against closely related Enterobacteriaceae. Current research focuses on production, release and uptake of these toxins by bacteria.
View Article and Find Full Text PDFImmediate and heterogeneous response of the LiaFSR two-component system of Bacillus subtilis to the peptide antibiotic bacitracin.
PLoS One
July 2013
Center for NanoScience, Ludwig-Maximilians-University, Fakultät für Physik, Munich, Germany.
Background: Two-component signal transduction systems are one means of bacteria to respond to external stimuli. The LiaFSR two-component system of Bacillus subtilis consists of a regular two-component system LiaRS comprising the core Histidine Kinase (HK) LiaS and the Response Regulator (RR) LiaR and additionally the accessory protein LiaF, which acts as a negative regulator of LiaRS-dependent signal transduction. The complete LiaFSR system was shown to respond to various peptide antibiotics interfering with cell wall biosynthesis, including bacitracin.
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