As ontologies are mostly manually created, they tend to contain errors and inconsistencies. In this paper, we present an automated computational method to audit symmetric concepts in ontologies by leveraging self-bisimilarity and linguistic structure in the concept names. Two concepts A and B are symmetric if concept B can be obtained from concept A by replacing a single modifier such as "left" with its symmetric modifier such as "right." All possible local structural types for symmetric concept pairs are enumerated according to their local subsumption hierarchy, and the pairs are further classified into Non-Matches and Matches. To test the feasibility and validate the benefits of this method, we computed all the symmetric modifier pairs in the Foundational Model of Anatomy (FMA) and selected six of them for experimentation. 9893 Non-Matches and 221 abnormal Matches with potential errors were discovered by our algorithm. Manual evaluation by FMA domain experts on 176 selected Non-Matches and all the 221 abnormal Matches found 102 missing concepts and 40 misaligned concepts. Corrections for them have currently been implemented in the latest version of FMA. Our result demonstrates that self-bisimilarity can be a valuable method for ontology quality assurance, particularly in uncovering missing concepts and misaligned concepts. Our approach is computationally scalable and can be applied to other ontologies that are rich in symmetric concepts.
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http://dx.doi.org/10.1016/j.jbi.2013.03.005 | DOI Listing |
Psychol Res
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School of Psychology, Central China Normal University (CCNU), Wuhan, 430079, China.
The serial dependence effect (SDE) is a perceptual bias where current stimuli are perceived as more similar to recently seen stimuli, possibly enhancing the stability and continuity of visual perception. Although SDE has been observed across many visual features, it remains unclear whether humans rely on a single mechanism of SDE to support numerosity processing across two distinct numerical ranges: subitizing (i.e.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
December 2024
Department of Prosthodontics, Dental and Craniofacial Bioengineering and Applied Biomaterials, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece. Electronic address:
Introduction: Α customized organ-on-a-chip microfluidic device was developed for dynamic culture of oral mucosa equivalents (Oral_mucosa_chip-OMC).
Materials And Methods: Additive Manufacturing (AM) was performed via stereolithography (SLA) printing. The dimensional accuracy was evaluated via microfocus computed tomography (mCT), the surface characteristics via scanning electron microscopy (SEM), while the mechanical properties via nanoindentation and compression tests.
Med Phys
December 2024
Department of Physics, Lakehead University, Thunder Bay, Ontario, Canada.
Background: This study investigates a multi-angle acquisition method aimed at improving image quality in organ-targeted PET detectors with planar detector heads. Organ-targeted PET technologies have emerged to address limitations of conventional whole-body PET/CT systems, such as restricted axial field-of-view (AFOV), limited spatial resolution, and high radiation exposure associated with PET procedures. The AFOV in organ-targeted PET can be adjusted to the organ of interest, minimizing unwanted signals from other parts of the body, thus improving signal collection efficiency and reducing the dose of administered radiotracer.
View Article and Find Full Text PDFBrain Nerve
January 2025
Department of Neurology, Graduate School of Medicine, Chiba University.
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) includes a number of clinical subtypes. The major phenotype is "typical CIDP," which is characterized by symmetric and "proximal and distal" muscle weakness. Due to historical changes in the concept of CIDP, multifocal motor neuropathy, anti-myelin-associated glycoprotein (anti-MAG) neuropathy, and autoimmune nodopathy were excluded.
View Article and Find Full Text PDFSci Total Environ
December 2024
Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1084, Prague 4, Czech Republic.
Exposure of cell cultures at air-liquid interface (ALI), mimicking i.e. human lung surface, is believed to be one of the most realistic means to model toxicity of complex mixtures of pollutants on human health.
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