Dermatofibrosarcoma protuberans (DFSP) successfully treated with sorafenib: case report.

Clin Sarcoma Res

Division of Hematology & Oncology, Clemenceau Medical Center, City Center Building, Suite 3 A, Avenue Nouvelle, P,O, Box 1076, Beirut, Jounieh, Lebanon.

Published: April 2013

DFSP is a locally invasive, slow-growing tumor of the subcutaneous tissue that rarely metastasizes but recurs frequently after surgical excision. We report herein a case of highly recurrent, locally invasive DFSP that failed both postoperative radiation therapy and complete trial of Imatinib, but was successfully treated with Sorafenib, which showed unprecedented response.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637545PMC
http://dx.doi.org/10.1186/2045-3329-3-5DOI Listing

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