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A Rare Case of Hidradenoma Papilliferum of the Vulva.

J Obstet Gynaecol India

June 2024

Apollo Hospital, Navi Mumbai, India.

Article Synopsis
  • - Hidradenoma Papilliferum is a rare but benign tumor found predominantly in the anogenital region of women aged 30-49, although it can also appear in atypical locations like the breast, ears, and eyelids, known as Ectopic Hidradenoma Papilliferum.
  • - The tumor arises from apocrine or mammary-like glands and is characterized by a firm nodule with no connection to the skin's surface, often described as having a flesh to red color and a frond-like structure upon examination.
  • - A case study highlights a 33-year-old woman who experienced a slow-growing nodule in her perineum for eight months; a biopsy confirmed the diagnosis
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A Rare Case of Ectopic Hidradenoma Papilliferum of the External Auditory Canal.

Cureus

May 2024

Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami, Miller School of Medicine, Miami, USA.

Article Synopsis
  • Hidradenoma papilliferum (HP) is a non-cancerous tumor that mainly affects middle-aged women and appears as a small, smooth, skin-colored nodule typically under 1 cm in size.
  • Though it usually occurs in the anogenital region, rare cases have been reported in other areas with modified apocrine glands, such as the head and neck.
  • This text presents a second case of an ectopic HP found in the external ear canal, specifically in the conchal bowl, adding to the very limited documentation in medical literature.
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Article Synopsis
  • The study focuses on a case of conjunctival apocrine hidrocystoma that developed 60 years after a strabismus surgery in a 71-year-old man, highlighting its clinical features.
  • The cystic lesion was diagnosed through surgical excision, revealing characteristic cell structures associated with apocrine hidrocystomas, and a review of seven similar cases found that all presented after age 50.
  • The findings suggest that previous trauma or surgery, like strabismus surgery, might lead to the development of apocrine hidrocystomas due to ectopic gland deposition.
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Rare and unusual occurrence of ectopic hidradenoma papilliferum in maxillofacial region.

J Oral Maxillofac Pathol

January 2021

Core Diagnostics Private Limited, Gurgaon, Haryana, India.

Hidradenoma Papilliferum (HP) is a rare, benign, cutaneous adnexal tumor of middle-aged females arising mainly in the apocrine sweat glands of perianal and genital region. Initially, HP was considered to be an apocrine sweat gland tumor however recent research showed that it descends from the anogenital mammary-like glands, HP can be regarded theoretically as the cutaneous complement of mammary intraductal papilloma. Nongenital HP is an infrequent manifestation, ectopic forms of this entity have been defined with bulk of them occurring on the head and neck region (60%) and 85% of cases being 1.

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Hidradenoma papilliferum (HP) is a benign pathologic finding that has been described primarily in the vulvar region. While thought to arise from ectopic tissue along the mammary line, it is now known to also arise from mammary-like anogenital glands (MLG), which are part of the normal anogenital cellular and glandular milieu. Previous work has demonstrated the relationship between HP and hormone receptors, but this has not been documented in a clinical setting.

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