Discussed is a case of male cancer patient whose initial lesion was a transitional cell carcinoma of the left renal pelves. A bladder tumor (TCC) was subsequently found 6 months after a left nephro-ureterectomy. After treatment of these tumors, the patient remained well for 8 years. An inoperable lung cancer (squamous cell carcinoma) then developed 6 months prior to death. The patient died of an aneurysmal rupture of the ascending aorta. At autopsy, 2 latent carcinomas were identified, one in the prostate and the their in the thyroid gland. If the renal pelvic and the bladder tumors and the lung carcinomas were all independent, this would seem to be a case of six-fold carcinoma.
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