Desulfonylation of tosyl amides through catalytic photoredox cleavage of N-S bond under visible-light irradiation.

Chem Asian J

Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, PR China.

Published: June 2013

AI Article Synopsis

  • A new desulfonylation method has been created for tosyl amides using visible light to promote the breaking of N-S bonds.
  • This method is efficient and allows for a wide variety of substrates and functional groups to be used.
  • It also produces excellent yields, making it a promising advancement in the field of chemistry.

Article Abstract

All lit up: A novel and efficient desulfonylation method of tosyl amides has been developed by means of visible-light-promoted reductive cleavage of N-S bonds. This method has a broad substrate scope, good functional group tolerance, and excellent yields.

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http://dx.doi.org/10.1002/asia.201300224DOI Listing

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