The study investigated the participation experiences of elderly women with hand limitations in a maketools-inspired activity for improving bottle openability and verified the usefulness of the results from this approach. Participatory design was used to stimulate participants' hands-on fabrication of new bottle lid concepts. Air-dry modeling clay, Crayola Model Magic® (Crayola LLC, 1100 Church Lane Easton, PA 18044-0431), clay modeling tools sets and empty bottles were the tools used to explore feasible and user-envisioned ideal lids that could potentially reduce hand pain and improve function when opening bottles. Twenty-five elderly women fully participated in the study. They generated 36 bottle lid design concepts. Qualitative analysis identified inclusion of four primary design features as follows: 1) surface texture; 2) increased leverage through lid shape or diameters; 3) increased contact surface with palm/fingers through lid shape or height; and 4) facilitation of alternative grip types. The major limitations of the study were inclusion of only women participants and healthier persons living in a retirement community. Future research is needed to investigate the bottle lid preferences of men and persons with more severe hand function living in places other than independent living communities.
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http://dx.doi.org/10.1002/oti.1348 | DOI Listing |
Cancer
February 2025
Departmental Unit of Molecular and Genomic Diagnostics, Genomics Core Facility, G-STeP, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Background: To date, 11 DNA polymerase epsilon (POLE) pathogenic variants have been declared "hotspot" mutations. Patients with endometrial cancer (EC) characterized by POLE hotspot mutations (POLEmut) have exceptional survival outcomes. Whereas international guidelines encourage deescalation of adjuvant treatment in early-stage POLEmut EC, data regarding safety in POLEmut patients with unfavorable characteristics are still under investigation.
View Article and Find Full Text PDFJ Cachexia Sarcopenia Muscle
February 2025
Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Background: Diaphragm thickness is a potential marker of sarcopenia in addition to muscle mass and strength at extremities. We aimed to clarify the descriptive epidemiology and prognostic significance of diaphragm thickness in the general population.
Methods: The study participants were 3324 community residents (mean age: 61.
Microsurgery
January 2025
Service de Chirurgie Plastique et Reconstructrice, Hôpital européen Georges-Pompidou, Paris, France.
Objective: The optimal method for maintaining intraoperative blood pressure during microsurgical procedures remains controversial. While intravenous fluid administration is essential, overfilling can lead to complications. Vasopressor agents are used cautiously due to their vasoconstrictive effects, which could potentially lead to flap failure.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Orthopedic Surgery, Affiliated Hospital of Xuzhou Medical University, 99 Huaihai Road, Xuzhou, Jiangsu, 221002, China.
Purpose: To compare the efficacy and safety of skip titanium plates combined with adjacent spinous process suture suspension versus continuous titanium plate fixation in cervical laminoplasty.
Methods: A retrospective analysis of 125 patients (62 men, 63 women, average age 60.9 ± 10.
J Orthop Surg Res
January 2025
Department of Rehabilitation, The Affiliated Hospital of Youjiang Medical University for Nationalities, No.18, Zhongshan 2nd Road, Baise, 533000, Guangxi Zhuang Autonomous Region, China.
Background: Osteoporosis (OP) frequently occurs in post-menopausal women, increasing the risk of fracture. Early screening OP could improve the prevention of fractures.This study focused on the significance of miR-208a-3p in diagnosing OP and development regulation, aiming to explore a novel biomarker and therapeutic target for OP.
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