Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/1346-8138.12089 | DOI Listing |
JID Innov
January 2025
Centre for Stem Cell and Regenerative Medicince, King's College London, London, United Kingdom.
Penile intraepithelial neoplasia (PeIN) and penile squamous cell carcinoma (PeSCC) are both thought to be associated with male genital lichen sclerosus and human papillomavirus (HPV) infection through dichotomous pathways: (i) undifferentiated PeIN and warty/basaloid PeSCC are thought to be HPV related, whereas (ii) differentiated PeIN and usual PeSCC are considered HPV independent. Tissue arrays were constructed from male genital lichen sclerosus, undifferentiated and differentiated PeIN, usual-type PeSCC, and unaffected tissues. Staining for p16 and for high-risk and low-risk HPV subtypes through RNAscope was performed.
View Article and Find Full Text PDFBMC Urol
January 2025
Urology Department HOGIP UCAD, Cheikh Anta Diop University, Dakar, Senegal.
Background: The inelasticity of dartos tissue and the regulation of collagen expression are significant factors in the pathophysiology of chordee associated with hypospadias. While the COL2A1:COL1A1 ratio is recognised as a measure of cell differentiation, there is yet to be a study specifically examining this ratio in hypospadias. The aim of this study was to determine the COL2A1:COL1A1 ratio.
View Article and Find Full Text PDFBMC Urol
December 2024
Pediatric Surgery Dept, Al-Azhar university, Cairo, Egypt.
Background: Complications after male circumcision are numerous and may be presented as an adhesion between the glans penis and the preputial remnants, these adhesions may acquire different forms and troublesome the affected children.
Patients And Methods: This is a retrospective study of 95 consecutive children of presumed glanular-preputial adhesions referred for correction of circumcision. They were assessed and classified as having either an early preputial adhesion or a well-formed skin bridge into 2 groups; group (A) who have a simple adhesion that was resolved through a conservative preputial adhesiolysis while those in the group (B) had a well-formed skin bridge, which deserves surgical correction.
Beijing Da Xue Xue Bao Yi Xue Ban
December 2024
Department of Urology, Beijing Jishuitan Hospital, Capital Medical Universitay, Beijing 100035, China.
Objective: To evaluate the surgical methods for treating distal urethral stricture.
Methods: The clinical data of 80 patients with distal urethral stricture in Beijing Jishuitan Hospital, Captial Medical University between January 2018 and December 2022 were retrospectively collected. Including male genital lichen sclerosus (MGLS) 33 cases, iatrogenic injury 25 cases, postoperative hypospadias 12 cases, and other causes such as trauma 10 cases.
Int Urol Nephrol
December 2024
Department of Surgery, Division of Urology, Rutgers New Jersey Medical School, 185 South Orange Avenue, Newark, NJ, 07103, USA.
Introduction: Panurethral strictures represent the most severe form within the anterior urethral stricture spectrum, requiring more technically complex repairs and resulting in poorer outcomes compared to localized anterior urethral strictures (penile or bulbar). This abstract aims to describe the distinct characteristics of patients with panurethral strictures in a low socioeconomic status population.
Methods: Patients presenting with localized anterior (penile or bulbar) or panurethral strictures at University Hospital in Newark, NJ, between 2021 and 2023 were retrospectively identified.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!